Fig. 4 | Nature Communications

Fig. 4

From: Self-interaction of NPM1 modulates multiple mechanisms of liquid–liquid phase separation

Fig. 4

Two-dimensional size-and-shape distribution analyses of the sedimentation velocity AUC data. a NPM1, b NPM1N240, c NPM1N188, and d NPM1CTD. The transformed velocity data are shown as contour plots (heat maps) of c(M, f/f0,) (top), c(s, f/f0) (middle), and c(s, M) (bottom) with 0 fringes/S (white) to maximum value fringes/S (red), with increasing color temperature indicating higher values. Velocity data were acquired at 50,000 rpm at 20 °C in buffer comprised of 10 mM Tris, pH 7.5, 150 mM NaCl, 2 mM DTT. The s w ,(f/f0) w , and M-values are listed in Supplementary Table 2

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