Fig. 5 | Nature Communications

Fig. 5

From: Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae

Fig. 5

Timeline of the leprosy treatment and emergence of drug resistance in the XDR strains. Mutated genes conferring resistance to the corresponding drugs are shown in red. Arrows span from the onset of disease to the end of treatment. Horizontal lines show the period when a drug was given. Dotted lines mean irregular treatment. CAM chloramphenicol, CLO clofazimine, DDS dapsone, DPT thiambutosine (diphenylthiourea), ETO ethionamide, INH isoniazid, KAN kanamycin, LVX levofloxacin, MIN minocycline, OFX ofloxacin, PTO protionamide, RIF rifampicin, SMP sulfamethoxypyridazine, SPX sparfloxacin, STR streptomycin, TZA thiozamin

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