Table 1 Loss of IL-6 in ∆122p53 mice reduces tumour incidence

From: 133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling

Comparison Genotype NEM Tumours χ2-statistic p-value
Group 1 ∆/∆ IL-6+/+ 2 26 0.144 0.704
Group 2 ∆/∆ IL-6+/− 1 8
Group 1 ∆/∆ IL-6+/+ 2 26 4.39 0.036*
Group 2 ∆/∆ IL-6−/− 6 14
Group 1 ∆/+ IL-6+/+ 2 26 2.712 0.01*
Group 2 ∆/+ IL-6+/− 6 20
Group 1 ∆/+ IL-6+/+ 2 26 5.943 0.015*
Group 2 ∆/+ IL-6−/− 7 13
  1. Summary of χ2-statistic and p-value for no evidence of malignancy (NEM) between the genotypes
  2. *p < 0.05 was considered to be significant