Fig. 1 | Nature Communications

Fig. 1

From: 133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling

Fig. 1

Reduced expression of pro-inflammatory cytokines in IL-6-deficient ∆122p53 mice. Serum from ∆122/∆122 IL-6+/+ (n = 3), ∆122/∆122 IL-6−/− (n = 3) and +/+ IL-6−/− (n = 3) mice was analysed using Bio-Plex Pro Mouse Cytokine 23-plex Array. Cytokine concentrations (pg/ml) are means ± s.e.m. Heteroscedastic one-tailed unpaired t-test was performed and p < 0.05 was considered significant. *p < 0.05, **p < 0.005 and ***p < 0.0005 are designated, respectively. ∆/∆ = ∆122/∆122

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