Fig. 5 | Nature Communications

Fig. 5

From: Lipoteichoic acid deficiency permits normal growth but impairs virulence of Streptococcus pneumoniae

Fig. 5

Impact of TacL deficiency on pneumococcal virulence. Survival of CD-1 mice after a intranasal infection with ~2.5 × 107 bioluminescent S. pneumoniae D39lux wild type, D39luxΔtacL, or the complemented mutant (D39ΔtacL pBAV-tacL) in the pneumonia model (n = 10) (see also Supplementary Fig. 14 for bioluminescence images). b Survival of CD-1 mice (n = 12) after intraperitoneal infection with ~3 × 103 pneumococci in the systemic infection model. **p < 0.01; ns not significant (Log-rank (Mantel–Cox) test)

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