Figure 4: Nature Communications

Fig. 4

From: Functional mapping and annotation of genetic associations with FUMA

Fig. 4

Chromatin interactions and eQTLs of BMI risk loci on chr. 16. The most outer layer is the Manhattan plot displaying SNPs with P-value < 0.05. Candidate SNPs are colored based on the highest r 2 to one of the independent significant loci (red: r 2 > 0.8, orange: r 2 > 0.6). Other SNPs are colored in gray. rsID of top SNPs per locus are labeled. The outer circle is the chromosome coordinate and genomic risk loci are highlighted in blue. Genes mapped by either Hi-C or eQTLs are shown on the inner circle. Genes mapped by Hi-C, eQTLs are colored orange and green, respectively. Genes mapped by both are colored red. Chromatin interaction and eQTLs are shown as links colored orange and green respectively