Fig. 2: | Nature Communications

Fig. 2

From: Functional mapping and annotation of genetic associations with FUMA

Fig. 2

Overview of prioritized genes from BMI GWAS by FUMA. Starting from the BMI GWAS summary statistics, boxes represent results of the SNP2GENE process. The annotated SNPs include all independent lead SNPs and SNPs which are in LD with these lead SNPs. Prioritized genes are divided into three categories; genes that are implicated by deleterious coding SNPs (colored pink), by eQTLs for these genes (colored blue), or by chromatin interactions (colored green). The prioritized genes are further categorized into previously reported genes (blue) and novel genes (red) prioritized genes by FUMA. *These genes were not prioritized by FUMA since they do not have either deleterious coding SNPs, eQTLs or chromatin interactions, although they are located within GWAS risk loci