Table 1 Target-related structure and in vivo function of PTs

From: Relationships between structure, in vivo function and long-range axonal target of cortical pyramidal tract neurons

Structure (cellular) AVG ± SD POm-Ps N = 7; n = 3 SC-Ps N = 5; n = 2 Pons-Ps N = 7; n = 3 Sp5C-Ps N = 8; n = 3 L5 PTs N = 27; n = 3 L5tt (PTs)a L5st (ITs)a
Depth (μm) 1042±105 1055±97 1131±110 1154±98 1110±131 1154±163 1035±165
Cells in L5 (% NeuN) 7 5 12 9 33 33 43
Cells in L5 (C2 column) 256±109 174±79 421±112 284±67 1135±367 1151 1500
Structure (dendritic) N = 5 N = 5 N = 5 N = 4 N = 22 N = 16a N = 18a
Total length (mm) 12.7±1.2 13.2±3.9 16.8±4.7 13.8±3.8 14.5±3.7 14.7±3.4 7.4±1.7
Basal length (mm) 5.0±0.9 5.2±2.0 6.2±1.5 5.3±2.4 5.5±1.7 6.8±2.5 4.2±1.2
Apical length (mm) 7.8±0.7 8.1±2.3 10.6±3.7 8.5±1.4 9.0±2.5 7.9±1.6 3.2±0.8
Total branch points (BPs) 66±3 77±18 98±24 90±15 84±19 86±23 35±11
Basal BPs 24±5 31±11 37±6 33±14 32±10 39±15 21±8
Apical BPs 42±3 47±9 61±19 57±4 52±13 47±12 14±6
Function (ongoing) AVG ± SE N = 5 N = 5 N = 5 N = 5 N = 43 N = 9b N = 12b
Spike rate (Hz) 7.2±1.6 1.3±0.6 1.8±1.1 4.3±1.0 3.5±0.5 3.5±0.5 1.1±0.1
100 Hz burst (% APs) 5.2±1.2 13.5±6.5 5.2±2.0 4.6±2.8 6.2±1.1   
200 Hz burst (% Aps) 2.1±0.6 6.2±3.6 0.4±0.3 1.5±0.8 2.2±0.6   
Function (evoked) N = 5 N = 5 N = 5 N = 5 N = 43   
Onset probability 0.66±0.09 0.23±0.12 0.38 ± 0.20 0.64±0.11 0.45±0.05   
Onset rate (Hz) 5.1±1.7 1.7±1.2 4.5±2.9 6.9±3.1 4.0±0.8   
Sustained rate (Hz) 0.8±1.4 2.3±1.1 3.3±2.1 3.3±1.6 2.1±0.8   
  1. a and b denote previously reported data, refs. 3, 20, respectively. N denotes sample size (i.e., number of brain slices or number of neurons); n denotes number of animals