Table 1 Antimycobacterial activities of 18

From: Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents

  M. smegmatis MC2 155 M. tuberculosis H37Rv
1 >126.5 98.9
2 >124.5 2.4
3/4 0.12 9.6
5 30.3 1.2
6/7 30.7 0.0098
8 30.7 1.2
aKan/bRif 1.7a 0.3b
  1. Note: Results expressed as MICs (μM)
  2. The anti-TB activities of compounds 18 were performed in triplicate, n = 3
  3. aKanamycin
  4. bRifampin