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Adulthood cosmetic and sexual outcomes of the patients who underwent hypospadias repair in childhood

International Journal of Impotence Research (2024)Cite this article

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Abstract

This study aimed to assess the cosmetic and sexual outcomes of childhood hypospadias repair after puberty. Among 672 patients who underwent hypospadias repair between 2001 and 2017, 243 sexually active patients were included in the study. At their last visit, cosmetic and sexual evaluation were done through the Penile Perception Score, the Hypospadias Objective Scoring Evaluation, IIEF, MSHQ-EjD. The levels of erectile dysfunction(ED) severity were determined according to erectile function domain of IIEF. The median follow-up after the last surgery was 16 [IQR (13–18)] years, and median patient age at the time of study was 19.67 [IQR(18–22)] years. Patients were divided into two subgroups as follows: Group I; Repairs using grafts (n = 120, 49.4%) and Group II; Graft-free repairs (n = 123, 50.6%). The rate of dissatisfaction with penile appearance was higher in Group I (16.7% vs. 4.9%, p = 0.003). Mild ED was more frequent in Group I (14.2% vs. 3.3%, p = 0.007); while none of the patients had either moderate or severe ED. Other domains of sexual function were observed to be similar in both groups. The need for unwanted interventions due to complications, and surgeries requiring grafts were found to be risk factors for ED development and dissatisfaction with penile appearance in adulthood. Those who underwent graft-free hypospadias repair experience better cosmetic and sexual outcomes when compared to grafted repairs, yet, satisfactory results were achieved in almost 90% of the grafted repairs.

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Data are available from the corresponding author on reasonable request.

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Author information

Authors and Affiliations

  1. Division of Pediatric Urology, Department of Urology, İstanbul University, İstanbul Faculty of Medicine, Istanbul, Turkey

    Ismail Selvi, M. İrfan Dönmez, Ahmet Barış Aydın, Tayfun Oktar & Orhan Ziylan

  2. Department of Urology, Koç University, School of Medicine, Istanbul, Turkey

    Tayfun Oktar

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  1. Ismail Selvi
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  2. M. İrfan Dönmez
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  3. Ahmet Barış Aydın
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Contributions

Ismail Selvi: Acquisition of data, Analysis and Interpretation of data, Statistical analysis, Literature. Search, Drafting of the manuscript. M. İrfan Dönmez: Conception and design, Administrative, Drafting of the manuscript, Critical. revision of the manuscript for important intellectual content. Ahmet Barış Aydın: Acquisition of data, Analysis and Interpretation of data. Tayfun Oktar: Conception and design, Administrative, Technical or material support, Critical revision of the manuscript for important intellectual content, Supervision. Orhan Ziylan: Administrative, Critical revision of the manuscript for important intellectual. content, Technical or material support, Supervision.

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Correspondence to Ismail Selvi.

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The authors declare no competing interests.

Ethical approval

The study received Institutional Review Board approval (IRB number: E-32588556-051-2438799). All procedures performed in our study were in accordance with the ethical standards of the local research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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A formal written informed consent was obtained from all individual participants included in the study.

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Selvi, I., Dönmez, M.İ., Aydın, A.B. et al. Adulthood cosmetic and sexual outcomes of the patients who underwent hypospadias repair in childhood. Int J Impot Res (2024). https://doi.org/10.1038/s41443-024-00971-x

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  • DOI: https://doi.org/10.1038/s41443-024-00971-x

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