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Cryoablation of the penile nerves for chronic penile pain


We present a unique case of a 39-year-old male with a 20-year history of chronic penile pain. Unfortunately, there are currently very limited reports on how best to manage chronic penile pain, as chronic penile pain is a diagnosis of exclusion without any apparent disease. Here, we describe our patient’s clinical presentation of chronic penile pain, history of previously failed medical and procedural treatments, and eventually completion of cryoablation of the penile nerves. In this case study, we demonstrated that targeted cryoablation of the penile nerves is a potential treatment option for chronic penile pain that failed medical management. We also discuss the anatomy and innervation of the penis as it relates to sensation of chronic penile pain and subsequent cryoablation of the penile nerves.

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Fig. 1: The cryotherapy probe shown above was localized ~1 cm above the dorsal penile junction in the suprapubic area.

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The data used to support the findings of this study are included within the article.


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BW carried out acquisition of data, analysis and interpretation of data, and drafted the paper. BC assisted with analysis and interpretation of data and helped draft the paper. CD performed the cryoablation procedure and assisted with edits to the paper. All authors have read and approved the final paper.

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Correspondence to Brittany Wordekemper.

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The authors declare no competing interests.

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Wordekemper, B., Clifton, B. & Deibert, C.M. Cryoablation of the penile nerves for chronic penile pain. Int J Impot Res (2022).

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