Abstract
The growing demand for glans penis augmentation (GPA) makes it a hot topic in the field of andrological surgery, albeit still widely debated. The lack of high supporting evidence and its technically challenging aspects are the main concerns. The aim of this study was to review the current literature about GPA in order to provide an easy and comprehensive overview of the topic. GPA is suitable for managing both cosmetic and functional issues. Counseling should be the cornerstone of the decision-making process. A thorough understanding of the glans anatomy and treatment strategies remain essential to safely and effectively address the patient’s needs. GPA can be performed using injectable fillers or surgical grafting. Glans-shaft penis asymmetries, small glans size, and loss of glans tumescence can be managed by both injectable fillers and surgery. On the other hand, patients with lifelong premature ejaculation can mainly benefit from using injectable fillers. Currently, available studies show promising results but are limited by small sample’s size and non-randomized design. Furthermore, treatment-related complications are poorly reported. The long-term efficacy and safety profiles of GPA techniques should be further investigated.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 8 print issues and online access
$259.00 per year
only $32.38 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Ahn ST, Il Kwak T, Park KS, Kim JJ, Moon DG. Complications of glans penis augmentation. Int J Impot Res. 2019;31:245–55. https://doi.org/10.1038/s41443-018-0097-4
Kim JJ, Kwak TI, Jeon BG, Cheon J, Moon DG. Human glans penis augmentation using injectable hyaluronic acid gel. Int J Impot Res. 2003;15:439–43. https://doi.org/10.1038/sj.ijir.3901044
Kim JJ, Kwak TI, Jeon BG, Cheon J, Moon DG. Effects of glans penis augmentation using hyaluronic acid gel for premature ejaculation. Int J Impot Res. 2004;16:547–51. https://doi.org/10.1038/sj.ijir.3901226
Kwak TI, Jin MH, Kim JJ, Moon DG. Long-term effects of glans penis augmentation using injectable hyaluronic acid gel for premature ejaculation. Int J Impot Res. 2008;20:425–8. https://doi.org/10.1038/ijir.2008.26
Abdallah H, Abdelnasser T, Hosny H, Selim O, Al-Ahwany A, Shamloul R. Treatment of premature ejaculation by glans penis augmentation using hyaluronic acid gel: a pilot study. Andrologia. 2012;44:650–3. https://doi.org/10.1111/j.1439-0272.2011.01244.x
Littara A, Palmieri B, Rottigni V, Iannitti T. A clinical study to assess the effectiveness of a hyaluronic acid-based procedure for treatment of premature ejaculation. Int J Impot Res. 2013;25:117–20. https://doi.org/10.1038/ijir.2013.13
Alahwany A, Ragab MW, Zaghloul A, Abdallah H, Mostafa T. Hyaluronic acid injection in glans penis for treatment of premature ejaculation: a randomized controlled cross-over study. Int J Impot Res. 2019;31:348–55. https://doi.org/10.1038/s41443-018-0104-9
Shaeer O. Shaeer’s glans augmentation technique: a pilot study. J Sex Med. 2012;9:3264–9. https://doi.org/10.1111/j.1743-6109.2012.02966.x
Testut L, Latarjet A, Allara E. Trattato di anatomia umana: anatomia descrittiva e microscopica, organogenesi. Milano: Edra;; 2017.
Wein AJ, Kolon TF, Partin AW, Dmochowski RR, Kavoussi LR, Peters CA. Campbell-walsh-wein urology. Twelfth edition review. Philadelphia: Elsevier, Inc; 2020.
Gray H, Standring S, Barni T. Anatomia del Gray: le basi anatomiche per la pratica clinica. Milano: Edra; 2017.
Kosseifi F, Chebbi A, Raad N, Ndayra A, El Samad R, Achkar K, et al. Glans penis augmentation using hyaluronic acid for the treatment of premature ejaculation: a narrative review. Transl Androl Urol. 2020;9:2814–20. https://doi.org/10.21037/tau-20-1026
Shaeer O. Supersizing the penis following penile prosthesis implantation. J Sex Med. 2010;7:2608–16. https://doi.org/10.1111/j.1743-6109.2010.01723.x
Verze P, Arcaniolo D, Palmieri A, Cai T, La Rocca R, Franco M, et al. Premature ejaculation among italian men: prevalence and clinical correlates from an observational, non-interventional, cross-sectional, epidemiological study (IPER). Sex Med. 2018;6:193–202. https://doi.org/10.1016/j.esxm.2018.04.005
Verze P, Arcaniolo D, Imbimbo C, Cai T, Venturino L, Spirito L, et al. General and sex profile of women with partner affected by premature ejaculation: results of a large observational, non-interventional, cross-sectional, epidemiological study (IPER-F). Andrology. 2018;6:714–9. https://doi.org/10.1111/andr.12545
Verze P, La Rocca R, Spirito L, Califano G, Venturino L, Napolitano L, et al. Premature ejaculation patients and their partners: arriving at a clinical profile for a real optimization of the treatment. Arch Ital Urol Androl. 2021;93:42–7. https://doi.org/10.4081/aiua.2021.1.42
Sexual and Reproductive Health | Uroweb n.d. https://uroweb.org/guideline/sexual-and-reproductive-health/ Accessed 17 Apr 2021. https://doi.org/10.1016/j.eururo.2021.06.007
Moon DG, Kwak TI, Kim JJ. Glans penis augmentation using hyaluronic acid gel as an injectable filler. World J Mens Health. 2015;33:50–61. https://doi.org/10.5534/wjmh.2015.33.2.50
Funding
The research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Author information
Authors and Affiliations
Contributions
Gianluigi Califano was responsible for writing the report, conducting the search, screening potentially eligible studies, extracting and analyzing data, and interpreting results. Davide Arcaniolo was responsible for editing the report and provided feedback on the report. Claudia Collà Ruvolo was responsible for writing and editing the report, analyzing data, and interpreting results. Celeste Manfredi was responsible for extracting and analyzing data. Francesco Smarrazzo was responsible for screening potentially eligible studies, updating reference lists. Simone Cilio was responsible for screening potentially eligible studies, updating reference lists. Paolo Verze was responsible for designing the review protocol, provided feedback on the report.
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Califano, G., Arcaniolo, D., Ruvolo, C.C. et al. Glans penis augmentation: when, how, and why?. Int J Impot Res 34, 343–346 (2022). https://doi.org/10.1038/s41443-021-00464-1
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41443-021-00464-1
This article is cited by
-
The effect of penis size on partner sexual satisfaction: a literature review
International Journal of Impotence Research (2023)
-
Comment on “Complications and outcomes following injection of foreign material into the male external genitalia for augmentation: a single centre experience and systematic review”
International Journal of Impotence Research (2023)
-
Take-home messages on male genital aesthetic surgery
International Journal of Impotence Research (2022)
-
#Penisenlargement on Instagram: a mixed-methods study
International Journal of Impotence Research (2022)
-
New trend in medicine: aesthetic genital surgery
International Journal of Impotence Research (2022)