Abstract
Radial artery forearm free-flap (RAFFF) phalloplasty is considered by most authors as the gold-standard technique for genital gender-affirming surgery (GGAS). RAFFF surgical complications have rarely been investigated, and the aim of this study and literature review is to analyse and focus on the surgical technique and its postoperative vascular complications. From May 2016 to January 2020, a consecutive series of 25 transgender men who underwent GGAS were enrolled in the present study. Age, BMI and smoking habits were recorded for all patients. Overall, vascular flap complications occurred in 20% of cases. Complete flap loss due to acute arterial thrombosis was recorded in a single case (4%). In 8% of cases, limited ventro-proximal arterial ischaemia was detected, while in the remaining 8% of cases, venous ventral ischaemia was reported. These results were compared with the current literature results. Indeed, from our analysis, the number of flap veins (<2) was the only predictive factor for vascular complications. In conclusion, RAFFF represents a reliable option for total phallic construction, leading to satisfactory results in terms of flap survival. To optimize the surgical outcomes, venous vascular drainage should be recommended.
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References
Rieger UM, Majenka P, Wirthmann A, Sohn M, Bozkurt A, Djedovic G. Comparative study of the free microvascular groin flap: optimizing the donor site after free radial forearm flap phalloplasty. Urology. 2016;95:192–6.
Monstrey S, Hoebeke P, Selvaggi G, Ceulemans P, Van Landuyt K, Blondeel P, et al. Penile reconstruction: is the radial forearm flap really the standard technique? Plast Reconstr Surg. 2009;124:510–8.
Morrison SD, Shakir A, Vyas KS, Kirby J, Crane CN, Lee GK. Phalloplasty: a review of techniques and outcomes. Plast Reconstr Surg. 2016;138:594–615.
Hage JJ, Bouman FG, de Graaf FH, Bloem JJ. Construction of the neophallus in female-to-male transsexuals: The Amsterdam experience. J Urol. 1993;149:1463–8.
Hage JJ, Bloem JJ. Review of the literature on construction of a neourethra in female-to-male transsexuals. Ann Plast Surg. 1993;30:278–86.
Song C, Wong M, Wong CH, Ong YS. Modifications of the radial forearm flap phalloplasty for female-to-male gender reassignment. J Reconstr Microsurg. 2011;27:115–20.
Rashid M, Tamimy MS. Phalloplasty: the dream and the reality. Indian J Plast Surg. 2013;46:283–93.
Sarıkaya S, Ralph DJ. Mystery and realities of phalloplasty: a systematic review. Turk J Urol. 2017;43:229–36.
Van Caenegem E, Verhaeghe E, Taes Y, Wierckx K, Toye K, Goemaere S, et al. Long-term evaluation of donor-site morbidity after radial forearm flap phalloplasty for transsexual men. J Sex Med. 2013;10:1644–51.
Monstrey S, Hoebeke P, Dont M, Selvaggi G, Hamdi M, Van Landuyt K, et al. Radial forearm phalloplasty: a review of 81 cases. Eur J Plast Surg. 2005;28:206–12.
Wirthmann AE, Majenka P, Kaufmann MC, Wellenbrock SV, Kasper L, Hüttinger S, et al. Phalloplasty in female-to-male transsexuals by Gottlieb and Levine’s free radial forearm flap technique—a long-term single-center experience over more than two decades. J Reconstr Microsurg. 2018;34:235–41.
Selvaggi G, Monstrey S, Hoebeke P, Ceulemans P, Van Landuyt K, Hamdi M, et al. Donor-site morbidity of the radial forearm free flap after 125 phalloplasties in gender identity disorder. Plast Reconstr Surg. 2006;118:1171–7. Oct.
Monstrey SJ, Ceulemans P, Hoebeke P. Sex reassignment surgery inthe female-to-male transsexual. Semin Plast Surg. 2011;25:229–44.
Doornaert M, Hoebeke P, Ceulemans P, T’Sjoen G, Heylens G, Monstrey S. Penile reconstruction with the radial forearm flap: an update. Handchir Mikrochir Plast Chir. 2011;43:208–14.
Garaffa G, Christopher NA, Ralph DJ. Total phallic reconstruction in female-to-male transsexuals. Eur Urol. 2010;57:715–22.
Leriche A, Timsit MO, Morel-Journel N, Bouillot A, Dembele D, Ruffion A. Long-term outcome of forearm flee-flap phalloplasty in the treatment of transsexualism. BJU Int. 2008;101:1297–300.
Selvaggi G, Dhejne C, Landen M, Elander A. The 2011 WPATH standards of care and penile reconstruction in female-to-male transsexual individuals. Adv Urol. 2012;2012:581712.
Chang LD, Buncke G, Slezak S, Buncke HJ. Cigarette smoking, plastic surgery, and microsurgery. J Reconstr Microsurg. 1996;12:467–74.
Müller-Richter UD, Driemel O, Mörtl M, Schwarz S, Zorger N, Wagener H, et al. The value of Allen’s test in harvesting a radial forearm flap: correlation of ex-vivo angiography and histopathological findings. Int J Oral Maxillofac Surg. 2008;37:672–4.
Hage JJ, de Graaf FH, Bouman FG, Bloem JJ. Sculpturing the glans in phalloplasty. Plast Reconstr Surg. 1993;92:157–61. Discussion 162.
Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 2015;4:1.
Song R, Gao Y, Song Y, Yu Y, Song Y. The forearm flap. Clin Plast Surg. 1982;9:21–6.
Chang TS, Hwang WY. Forearm flap in one-stage reconstruction of the penis. Plast Reconstr Surg. 1984;74:251–8.
Gilbert DA, Schlossberg SM, Jordan GH. Ulnar forearm phallic reconstruction and penile reconstruction. Microsurgery. 1995;16:314–21.
Dabernig J, Shelley OP, Cuccia G, Schaff J. Urethral reconstruction using the forearm free flap: experience in oncologic cases and gender reassignment. Eur Urol. 2007;52:547–54.
Gottlieb LJ, Levine LA. A new design for the radial forearm freeflap phallic construction. Plast Reconstr Surg. 1993;92:276. Discussion 284.
Cheng KX, Hwang WY, Eid AE, Wang SL, Chang TS, Fu KD. Analysis of 136 cases of reconstructed penis using various methods. Plast Reconstr Surg. 1995;95:1070–80. Discussion 1081–4.
Hage JJ, Bloem JJ, Suliman HM. Review of the literature on techniques for phalloplasty with emphasis on the applicability in female-to-male transsexuals. J Urol. 1993;150:1093–8.
De Wolf E, Claes K, Sommeling CE, Opsomer D, Cherubino M, Vieni S, et al. Free bipedicled radial forearm and posterior interosseous artery perforator flap phalloplasty. J Sex Med. 2019;16:1111–7.
Acknowledgements
We would like to express our great appreciation to all physicians involved in this study for the great interest demonstrated towards this ambitious project and the accuracy demonstrated in collecting data.
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Falcone, M., Preto, M., Timpano, M. et al. The surgical outcomes of radial artery forearm free-flap phalloplasty in transgender men: single-centre experience and systematic review of the current literature. Int J Impot Res 33, 737–745 (2021). https://doi.org/10.1038/s41443-021-00414-x
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DOI: https://doi.org/10.1038/s41443-021-00414-x
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