Abstract
Metoidioplasty denotes the creation of a neophallus out of the hormonally hypertrophied clitoris. Construction of an esthetically acceptable male-like genitalia while enabling micturition in standing position are the primary goals. Herein, we aim to review the literature regarding masculinizing gender-affirming genital surgery in the form of metoidioplasty, focusing on the steps related to urethral lengthening and reconstruction, and describe the authors’ preferred surgical technique. Clitoral release, division of the urethral plate, native urethral lengthening with anterior vaginal wall flap, and neourethral tubularization using a combination of buccal mucosa graft and labia minora flap(s) seem to provide the best result in terms of urinary outcomes. This is reflected in a greater urethral length, higher probability of standing micturition, and lower incidence of fistula. Urethral complications, which can be encountered in up to 15% of the patients, may necessitate additional procedures. Some of the studies have reported successful penetrative intercourse following metoidioplasty. Case series about different metoidioplasty techniques do not allow head-to-head comparison due to non-standardized reporting and outcome assessment. Metoidioplasty can be offered to transgender men with sufficiently hypertrophied clitoris who wish to avoid a complicated, multistage, flap-based total phalloplasty, or for those individuals considering phalloplasty at a later date.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 8 print issues and online access
$259.00 per year
only $32.38 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC: American Psychiatric Association; 2013.
Conway L, Winter S. How many trans people are there? A 2011 update incorporating new data. http://www.transgenderasia.org/paper-how-many-trans-people-arethere.htm. Accessed 14 Feb 2019.
Dhejne C, Öberg K, Arver S, Landen M. An analysis of all applications for sex reassignment surgery in Sweden, 1960- 2010: prevalence, incidence, and regrets. Arch Sex Behav. 2014;43:1535–45.
De Cuypere G, Vanhemelrijck M, Michel A, Carael B, Heylens G, Rubens R, et al. Prevalence and demography of transsexualism in Belgium. Eur Psychiatry. 2007;22:137–41.
Meier SC, Labuski CM. Demographics of the transgender population. In: Baumle, Amanda K. editor. International handbook on the demography of sexuality. Dordrecht, The Netherlands: Springer; 2013. p. 289–327.
Hess J, Rossi Neto R, Panic L, Rübben H, Senf W. Satisfaction with male-to-female gender reassignment surgery. Dtsch Arztebl Int. 2014;111:795–801.
van der Sluis WB, Bouman M-B, de Boer NKH, Buncamper M, van Bodegraven AA, Neefjes-Borst EA, et al. Long-term follow-up of transgender women after secondary intestinal vaginoplasty. J Sex Med. 2016;13:702–10.
Frey JD, Poudrier G, Chiodo MV, Hazen A. An update on genital reconstruction options for the female-to-male transgender patient: a review of the literature. Plast Reconstr Surg. 2017;139:728–37.
Selvaggi G, Dhejne C, Landen M, Elander A. The 2011 WPATH standards of care and penile reconstruction in female-to-male transsexual individuals. Adv Urol. 2012;2012:581712.
Djordjevic ML. Novel surgical techniques in female to male gender confirming surgery. Transl Androl Urol. 2018;7:628–38.
Hage JJ, De Graaf FH. Addressing the ideal requirements by free flap phalloplasty: some reflections on refinements of technique. Microsurgery. 1993;14:592–8.
Hadj-Moussa M, Agarwal S, Ohl DA, Kuzon WM Jr. Masculinizing genital gender confirmation surgery. Sex Med Rev. 2019;7:141–55.
Djinovic RP. Metoidioplasty. Clin Plast Surg. 2018;45:381–6.
Lebovic GS, Laub DR. Metoidioplasty. In: Ehrlich RM, Alter GJ, editors. Reconstructive and plastic surgery of the external genitalia. Philadelphia: W.B. Saunders Co; 1999. p. 355–60.
Hage JJ, Metoidoioplasty. An alternative phalloplasty technique in transsexuals. Plast Reconstr Surg. 1996;97:161–7.
Perovic SV, Djordjevic M. Metoidioplasty: a variant of phalloplasty in female transsexuals. BJU Int. 2003;92:981–5.
Hage JJ, Turnhout WM. Long-term outcome of metoidioplasty in 70 female to male transsexuals. Ann Plast Surg. 2006;57:312–6.
Takamatsu A, Harashina T. Labial ring flap: a new flap for metaidoioplasty in female-to-male transsexuals. J Plast Reconstr Aesthet Surg. 2009;62:318–25.
Djordjevic ML, Bizic M, Stanojevic D, Bumbasirevic M, Kojovic V, Majstorovic M, et al. Urethral Lengthening in metoidioplasty (female-to-male sex reassignment surgery) by combined buccal mucosa graft and labia minora flap. Urology. 2009;74:349–53.
Djordjevic ML, Bizic MR. Comparison of two different methods for urethral lengthening in female to male (metoidioplasty) surgery. J Sex Med. 2013;10:1431–8.
Djordjevic ML, Stanojevic D, Bizic M, Kojovic V, Majstorovic Vujovic, et al. Metoidioplasty as a single stage sex reassignment surgery in female transsexuals: Belgrade experience. J Sex Med. 2009;6:1306–13.
Stojanovic B, Bizic M, Bencic M, Kojovic V, Majstorovic M, Jeftovic M, et al. One-stage gender-confirmation surgery as a viable surgical procedure for female-to-male transsexuals. J Sex Med. 2017;14:741–6.
Vukadinovic V, Stojanovic B, Majstorovic M, Milosevic A. The role of clitoral anatomy in female to male sex reassignment surgery. Sci World J. 2014;2014:437378.
Frey JD, Poudrier G, Chiodo MV, Hazen A. A systematic review of metoidioplasty and radial forearm flap phalloplasty in female-to-male transgender genital reconstruction: Is the “Ideal” neophallus an achievable goal? Plast Reconstr Surg Glob Open. 2016;4:e1131.
Kerckhof ME, Kreukels BPC, Nieder TO, Becker-Hebly I, van de Grift TC, Staphorsius AS, et al. Prevalence of sexual dysfunctions in transgender persons: results from the ENIGI follow-up study. J Sex Med. 2019;16:2018–29.
Cohanzad S. Extensive metoidioplasty as a technique capable of creating a compatible analogue to a natural penis in female transsexuals. Aesth Plast Surg. 2016;40:130–8.
Djordjevic ML, Stojanovic B, Bizic M. Metoidioplasty: techniques and outcomes. Transl Androl Urol. 2019;8:248–53.
Nikolavsky D, Hughes M, Zhao LC. Urologic complications after phalloplasty or metoidioplasty. Clin Plast Surg. 2018;45:425–35.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Kocjancic, E., Acar, O., Talamini, S. et al. Masculinizing genital gender-affirming surgery: metoidioplasty and urethral lengthening. Int J Impot Res 34, 120–127 (2022). https://doi.org/10.1038/s41443-020-0259-z
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41443-020-0259-z
This article is cited by
-
Overview on metoidioplasty: variants of the technique
International Journal of Impotence Research (2021)
-
Surgical repair of urethral complications after metoidioplasty for genital gender affirming surgery
International Journal of Impotence Research (2021)