Penile prosthesis infection remains a rare but devastating complication of implantation. Historically, management of device infection was always extirpation. While certainly effective, device removal leaves an unhappy patient with a shortened penis. In this last part of a three-part series on the topic of penile prosthesis infection, we seek to highlight new and emerging ideas of infection management which have allowed surgeons the option of preserving the implanted status in select patients.
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 8 print issues and online access
$259.00 per year
only $32.38 per issue
Rent or buy this article
Prices vary by article type
Prices may be subject to local taxes which are calculated during checkout
Holloway FB, Farah RN. Intermediate term assessment of the reliability, function and patient satisfaction with the AMS700 Ultrex penile prosthesis. J Urol. 1997;157:1687–91.
Köhler TS, Wen L, Wilson SK. Penile implant device infection part 1: fact or fiction. Int J Impot Res. 2020. online ahead of print.
Mulcahy JJ, Köhler TS, Wen L, Wilson SK. Penile implant infections part 2: infection retardant coatings have changed the game. Int J Impot Res. 2020. online ahead of print.
Wilson SK, Costerton W. Biofilm and penile prosthesis infections in the era of coated implants: a review. J Sex Med. 2012;9:44–53.
Wolter CE, Hellstrom WJ. The hydrophilic-coated inflatable penile prosthesis: 1-year experience. J Sex Med. 2004;1:221–4.
Kava BR, Kanagarajah P, Ayyathurai P. Contemporary revision penile prosthesis surgery is not associated with a high risk of implant colonization or infection: a single-surgeon series. J Sex Med. 2011;8:1540–6.
Mulcahy JJ. Current approach to the treatment of penile implant infections. Ther Adv Urol. 2010;2:69–75.
Kim JC, Lunati FP, Khan SA, Waltzer WC. T-tube drainage of infected penile corporeal chambers. Urology. 1995;45:514–5.
Maatman TJ, Montague DK. Intracorporeal drainage after removal of infected penile prostheses. Urology. 1984;23:184–5.
Lopategui DM, Balise RR, Bouzoubaa LA, Wilson SK, Kava BR. The impact of immediate salvage surgery on corporeal length preservation in patients presenting with penile implant infections. J Urol. 2018;200:171–7.
Canguven O, Talib RA, Campbell J, De Young L, El Ansari W, Al-Ansari A. Is the daily use of vacuum erection device for a month before penile prosthesis implantation beneficial? a randomized controlled trial. Andrology. 2017;5:103–6.
Köhler TK, Gupta NK, Wilson SK. Wilson’s pearls perils and pitfalls of penile prosthesis surgery. Fort Smith AR: Calvert McBride; 2018.
Wilson SK, Simhan J Gross M. Cylinder insertion into scarred corporal bodies: prosthetic urology’s most difficult challenge. Int J Impot Res. 2020. online ahead of print.
Caire AA, Boonjindasup A, Hellstrom WJ. Does a replacement or revision of an inflatable penile prosthesis lead to decreased patient satisfaction? Int J Impot Res. 2011;23:39–42.
Silverstein AD, Henry GD, Evans B, Pasmore M, Simmons CJ, Donatucci CF. Biofilm formation on clinically noninfected penile prostheses. J Urol. 2006;176:1008–11.
Darouiche RO, Bell AJ, Boone TB, Brock G, Broderick GA, Burnett AL, et al. North American consensus document on infection of penile prostheses. Urology. 2013;82:937–42.
Olds C, Spataro E, Li K, Kandathil C, Most SP. Postoperative antibiotic use among patients undergoing functional facial plastic and reconstructive surgery. JAMA Facial Plast Surg. 2019;21:491–7.
Gupta NK, Sulaver R, Welliver C, Kottwitz M, Frederick L, Dynda D, et al. Scrotoplasty at time of penile implant is at high risk for dehiscence in diabetics. Sex Med. 2019;4:602–8.
Henry GD, Price G, Pryor M, Greenfield J, Jones L, Perito P, et al. Observation of local clinical penile prostheses infections instead of immediate salvage rescue/removal: multicenter study with surprising results; Abstract: PD20-04. J Urol. 2014;191 Supplement: E612–3.
Habous M, Farag M, Williamson B, Laban O, Mahmoud S, Abdelwahab O, et al. Conservative therapy is effective option in patients with localized infection after penile implant surgery. Sex Med. 2016;1:972–6.
Cotta BH, Butcher M, Welliver C, McVary K, Köhler T. Two fungal infections of inflatable penile prostheses in diabetics. Sex Med. 2015;4:339.
Rezaee ME, Towe M, Osman MM, Huynh LM, El-Khatib FM, Andrianne R, et al. Multicenter investigation of the micro-organisms involved in penile prosthesis infection: an analysis of the efficacy of the AUA and EAU guidelines for penile prosthesis prophylaxis. J Sex Med. 2017;14:455–63.
Mulcahy JJ. Long-term experience with salvage of infected penile implants. J Urol. 2000;163:481–2.
Brant MD, Ludlow JK, Mulcahy JJ. The prosthesis salvage operation: immediate replacement of the infected penile prosthesis. J Urol. 1996;155:155–7.
Knoll LD. Penile prosthetic infection: management by delayed and immediate salvage techniques. Urology. 1998;52:287–90.
Bryan DE, Mulcahy JJ, Simmons GR. Salvage procedure for infected noneroded artificial urinary sphincters. J Urol. 2002;168:2464–6.
Pan S, Rodriguez D, Thirumavalavan N, Gross MS, Eid JF, Mulcahy J, et al. The use of antiseptic solutions in the prevention and management of penile prosthesis infections: a review of the cytotoxic and microbiological effects of common irrigation solutions. J Sex Med. 2019;16:781–90.
Manka MG, Yang D, Andrews J, Chalmers B, Hebert K, Köhler TS, Trost L. Intraoperative use of Betadine irrigation is associalted with 9-fold increased liklihood of penile prosthesis infection: results from a retrospective case controled study. J Sex Med. 2020;8:422–7.
Zargaroff S, Sharma V, Berhanu D, Pearl JA, Meeks JJ, Dupree JM, et al. National trends in the treatment of penile prosthesis infections by explantation alone vs. immediate salvage and reimplantation. J Sex Med. 2014;11:1078–85.
Gross MS, Phillips EA, Balenm A, Eid JF, Yang C, Simon R, et al. The malleable implant salvage technique: infection outcomes after mulcahy salvage procedure and replacement of infected inflatable penile prosthesis with malleable prosthesis. J Urol. 2016;195:694–7.
Parsons CL, Stein PC, Dobke MK, Virden CP, Frank DH. Diagnosis and therapy of subclinically infected prostheses. Surg Gynecol Obstet. 1993;177:504–6.
Lujan S, Rogel R, Broseta E, Boronat F. local treatment of penile prosthesis infection as alternative to immediate salvage surgery. Sex Med. 2016;4:e255–8.
Henry GD, Wilson SK, Delk JR, Carson CC, Silverstein A, Cleves MA, et al. Penile prosthesis cultures during revision surgery: a multicenter study. J Urol. 2004;172:153–6.
Henry GD, Wilson SK, Delk JR, Carson CC, Wiygul J, Tornehi C, et al. Revision washout decreases penile prosthesis infection in revision surgery: a multicenter study. J Urol. 2005;173:89–92.
Kohler TS, Modder JK, Dupree JM, Bush NC, McVary KT. Malleable implant substitution for the management of penile prosthesis pump erosion: a pilot study. J Sex Med. 2009;6:1474–8.
Conflict of interest
TSK: Consultant Boston Scientific and Coloplast. LW: Nothing to declare. SKW: Consultant AMT, Coloplast, International Medical Devices. Lecturer Boston Scientific.
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
About this article
Cite this article
Köhler, T.S., Wen, L. & Wilson, S.K. Penile implant infection part 3: the changing spectrum of treatment. Int J Impot Res 35, 512–518 (2023). https://doi.org/10.1038/s41443-020-00382-8
This article is cited by
International Journal of Impotence Research (2023)