Perspective | Published:

Sildenafil/Viagra in the treatment of premature ejaculation

International Journal of Impotence Researchvolume 31pages6570 (2019) | Download Citation

Abstract

The arrival of Pfizer’s blue pill Sildenafil in 1998 brought a great relief both to patient and physician signalling the start of a great era of medical therapy in sexual medicine. Since then the sexual medicine experts have been prescribing sildenafil in erectile dysfunction with acceptable minor adverse events. But the use of sildenafil in premature ejaculation (PE) is still debated. 2018 being the 20th anniversary of sildenafil, we have compiled interesting facts about the role of sildenafil in PE from various original articles, systematic reviews, meta-analyses, economic brochures and sexual medicine committee guidelines. The major issues in most of these studies were the heterogeneity in the definition of PE and estimating the exact ejaculatory latency time. This perspective article highlights the positive role of sildenafil in the management of PE (even without ED) with acceptable adverse events. Now that we have a standardised definition of PE from International Society of Sexual Medicine (ISSM) and a psychogenic component in PE definition, more randomised placebo-controlled studies are required to further establish its role.

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Author information

Affiliations

  1. Department of Urology, NU Hospitals, Bangalore, India

    • Pramod Krishnappa
  2. Department of Urology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain

    • Pramod Krishnappa
    • , Esau Fernandez-Pascual
    • , Joaquin Carballido
    •  & Juan Ignacio Martinez-Salamanca

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The authors declare that they have no conflict of interest.

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Correspondence to Pramod Krishnappa.

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https://doi.org/10.1038/s41443-018-0099-2