Article | Published:

Sexual dysfunction and distress in premenopausal women with migraine: association with depression, anxiety and migraine-related disability

International Journal of Impotence Researchvolume 30pages265271 (2018) | Download Citation

Abstract

Migraine is a chronic disorder associated with impaired quality of life as well as sexual function. However, data about the sexual distress in women with migraine were lacked.This study aimed to determine the incidence and associated risk factors of both sexual function and distress in premenopausal women with migraine. Sixty-nine women diagnosed with migraine were included. Sexual function and distress were assessed by Female sexual function index (FSFI) and Female sexual distress scale-revised (FSDS-R), respectively. Depression and anxiety were investigated by Hospital depression and anxiety scale (HADS). Migraine related disability was evaluated by Migraine disability assessment scale (MIDAS) and average severity of pain was determied by Visual analog scale (VAS). Fifty-five women reported to have sexual dysfunction. Any headache-related feature including MIDAS and VAS scores, depression or anxiety was found to be related with sexual dysfunction. Sexual distress was noted in 37 cases, and depression, VAS and MIDAS scores were significantly higher in women with sexual distress. This study showed that women with migraine should be screened both for sexual dysfunction and distress to help clinicians dealing with sexual medicine to improve the standart of patient care in their regular practice. Special attention should be given to the ones whose MIDAS and VAS scores were high and who had depression.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    Smith AM, Lyons A, Ferris JA, Richters J, Pitts MK, Shelley JM, et al. Incidence and persistence/recurrence of women’s sexual difficulties: findings from the Australian longitudinal study of health and relationships. J Sex Marital Ther. 2012;38:378–93.

  2. 2.

    Laumann EO, Paik A, Rosen RC. Sexual dysfunction in the United States: prevalence and predictors. JAMA. 1999;281:537–44.

  3. 3.

    Basson R, Berman J, Burnett A, Derogatis L, Ferguson D, Fourcroy J, et al. Report of the international consensus development conference on female sexual dysfunction: definitions and classifications. J Urol. 2000;163:888–93.

  4. 4.

    McCabe MP, Sharlip ID, Atalla E, Balon R, Fisher AD, Laumann E, et al. Definitions of sexual dysfunctions in women and men: a consensus statement from the fourth international consultation on sexual medicine 2015. J Sex Med. 2016;13:135–43.

  5. 5.

    Clayton AH, Groth J. Etiology of female sexual dysfunction. Women’s Health. 2013;9:135–7.

  6. 6.

    Schwaiger J, Kiechl S, Seppi K, Sawires M, Stockner H, Erlacher T, et al. Prevalence of primary headaches and cranial neuralgias in men and women aged 55–94 years (Bruneck Study). Cephalalgia. 2009;29:179–87.

  7. 7.

    Zarifoglu M, Siva A, Hayran O. An epidemiological study of headache in Turkey: a nationwide survey. Neurology. 1998;50(Suppl 4):80–5. The Turkish headache epidemiology study group

  8. 8.

    Kwan KS, Roberts LJ, Swalm DM. Sexual dysfunction and chronic pain: the role of psychological variables and impact on quality of life. Eur J Pain. 2005;9:643–52.

  9. 9.

    Abdollahi M, Toghae M, Raisi F, Saffari E. The prevalence of female sexual dysfunction among migraine patients. Iran J Neurol. 2015;14:8–11. Jan 5

  10. 10.

    Solmaz V, Ceviz A, Aksoy D, Cevik B, Kurt S, Gencten Y, et al. Sexual dysfunction in women with migraine and tension-type headaches. Int J Impot Res. 2016;28:201–4.

  11. 11.

    Ifergane G, Ben-Zion IZ, Plakht Y, Regev K, Wirguin I. Not only headache: higher degree of sexual pain symptoms among migraine sufferers. J Headache Pain. 2008;9:113–7.

  12. 12.

    Bestepe E, Cabalar M, Kucukgoncu S, Calıkusu C, Ornek F, Yayla V, et al. Sexual dysfunction in women with migraine versus tension-type headaches: a comparative study. Int J Impot Res. 2011;23:122–7.

  13. 13.

    Eraslan D, Yalınay Dikmen P, Ilgaz Aydınlar E, Incesu C. The relation of sexual function to migraine-related disability, depression and anxiety in patients with migraine. J Headache Pain. 2014;15:32.

  14. 14.

    Dogan VB, Dağdeviren H, Dirican A, Dirican AC, Tutar NK, Yayla VA, et al. Hormonal effect on the relationship between migraine and female sexual dysfunction. Neurol Sci. 2017;38(9):1651-5.

  15. 15.

    Antonaci F, Nappi G, Galli F, Manzoni GC, Calabresi P, Costa A. Migraine and psychiatric comorbidity: a review of clinical findings. J Headache Pain. 2011;12:115–25.

  16. 16.

    American psychiatric association. Diagnostic and statistical manual of mental disorders (DSM-5). 5th ed. Washington, DC: American Psychiatric Association; 2013.

  17. 17.

    Nappi RE, Terreno E, Tassorelli C, Sances G, Allena M, Guaschino E, et al. Sexual function and distress in women treated for primary headaches in a tertiary university center. J Sex Med. 2012;9:761–9.

  18. 18.

    Mushtaq AY. Coping strategies used by post-menopausal women in srinagar district of kashmir valley. Anthropologist. 2014;17:1003–6.

  19. 19.

    Beigi FF. A comparative study on sexual function before and after menopause. Iran J Nurs Midwifery. 2012;17:72–5.

  20. 20.

    International Headache Society. The international classification of headache disorders. Cephalalgia. 2004;24:1–151. 2nd edn.

  21. 21.

    Ertas M, Siva A, Dalkara T, Uzuner N, Dora B, Inan L, et al. Validity and reliability of the Turkish migraine disability assessment (MIDAS) questionnaire. Headache. 2004;44:786–93.

  22. 22.

    Aygin D, Aslan FE. Turkish adaptation of the female sexual function index Türkiye Klinikleri. J Med Sci. 2005;25:393–9.

  23. 23.

    Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R, et al. The Female sexual function index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2000;26:191–208.

  24. 24.

    Derogatis L, Clayton A, Lewis-D’Agostino D, Wunderlich G, Fu Y. Validation of the female sexual distress scale—revised for assessing distress in women with hypoactive sexual desire disorder. J Sex Med. 2008;5:357–64.

  25. 25.

    Aydın S, Onaran ÖI, Topalan K, Aydın ÇA, Dansuk R. Development and validation of Turkish version of the female sexual distress scale-revised. Sex Med. 2016 Mar;4:e43–50.

  26. 26.

    Derogatis LR, Rosen R, Leiblum S, Burnett A, Heiman J. The female sexual distress scale (FSDS): initial validation of a standardized scale for assessment of sexually related personal distress in women. J Sex Marital Ther. 2002;28:317–30. Jul-Sep

  27. 27.

    Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361–70.

  28. 28.

    Burri A, Spector T. Recent and lifelong sexual dysfunction in a female UK population sample: prevalence and risk factors. J Sex Med. 2011;8:2420–30.

  29. 29.

    Witting K, Santtila P, Rijsdijk F, Varjonen M, Jern P, Johansson A, et al. Correlated genetic and non-shared environmental influences account for the co-morbidity between female sexual dysfunctions. Psychol Med. 2009;39:115–27.

  30. 30.

    Ghajarzadeh M, Jalilian R, Togha M, Azimi A, Hosseini P, Babaei N. Depression, poor sleep, and sexual dysfunction in migraineurs women. Int J Prev Med. 2014;5:1113–8.

  31. 31.

    Bond DS, Pavlović JM, Lipton RB, Graham Thomas J, Digre KB, Roth J, et al. Sexual dysfunction in women with migraine and overweight/obesity: relative frequency and association with migraine severity. Headache. 2017;57:417–27.

  32. 32.

    Kennedy SH, Rizvi S. Sexual dysfunction, depression, and the impact of antidepressants. J Clin Psychopharmacol. 2009;29:157–64.

  33. 33.

    Vannier SA, Rosen NO. Sexual distress and sexual problems during pregnancy: associations with sexual and relationship satisfaction. J Sex Med. 2017;14:387–95.

  34. 34.

    Hayes RD. Assessing female sexual dysfunction in epidemiological studies: why is it necessary to measure both low sexual function and sexually related distress? Sex Health. 2008;5:215–8.

Download references

Acknowledgements

We would like to acknowledge Fatih Mehmet Yazar, MD for beneficial consultation on the statistical analyses.

Author information

Affiliations

  1. Department of Urology, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey

    • Faruk Kucukdurmaz
    •  & Sefa Resim
  2. Department of Neurology, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey

    • Yılmaz Inanc
  3. Department of Neurology, Gaziantep University, Gaziantep, Turkey

    • Yusuf Inanc

Authors

  1. Search for Faruk Kucukdurmaz in:

  2. Search for Yılmaz Inanc in:

  3. Search for Yusuf Inanc in:

  4. Search for Sefa Resim in:

Conflict of interest

The authors declare that they have no conflict of interest.

Corresponding author

Correspondence to Faruk Kucukdurmaz.

About this article

Publication history

Received

Revised

Accepted

Published

DOI

https://doi.org/10.1038/s41443-018-0049-z