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A case of adrenaline-predominant paraganglioma diagnosed with a state of shock after glucagon injection

Hypertension Research volume 43, pages 473–475 (2020)Cite this article

Pheochromocytoma-paraganglioma (PPGL), a catecholamine-secreting tumor, is a rare and curable cause of hypertension, with frequent complications of headache, sweating, palpitation, and hyperhidrosis. PPGL may precipitate hypertensive crisis with several agents, such as contrast medium, glucagon, and metoclopramide. We report a case of a recurrent right retroperitoneal paraganglioma that was diagnosed by hypertensive crisis with glucagon administration for pretreatment for endoscopic examination 17 years after surgery on a right adrenal pheochromocytoma.

A 75-year-old woman who had headache, paroxysmal hypertension, and hyperhidrosis for 3 years was diagnosed with a pheochromocytoma from an endocrine profile and computed tomography (CT) scan, which showed a right adrenal tumor in 1999.

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Authors and Affiliations

  1. Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University, Yufu, 879-5593, Japan

    Hiroshi Nakama, Mitsuhiro Okamoto, Koro Gotoh, Takayuki Masaki & Hirotaka Shibata

  2. Advanced Trauma, Emergency and Critical Care Center, Faculty of Medicine, Oita University, Yufu, 879-5593, Japan

    Keiko Kurosawa

  3. Department of Urology, Faculty of Medicine, Oita University, Yufu, 879-5593, Japan

    Hiromitsu Mimata

  4. Department of Pathology, Faculty of Medicine, Oita University, Yufu, 879-5593, Japan

    Tsutom Daa

  5. Laboratory of Laboratory/Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Ibaraki, 305-8577, Japan

    Kazuhiro Takekoshi

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  1. Hiroshi Nakama
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Correspondence to Hirotaka Shibata.

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Nakama, H., Okamoto, M., Kurosawa, K. et al. A case of adrenaline-predominant paraganglioma diagnosed with a state of shock after glucagon injection. Hypertens Res 43, 473–475 (2020). https://doi.org/10.1038/s41440-020-0400-x

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