Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Umami taste disorder is a novel predictor of obesity

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    Kelly JJ Jr. Multifocal motor neuropathy. Neurology 1992;42(11):2230–2231.

    Article  Google Scholar 

  2. 2.

    Morita R, Ohta M, Hayabuchi H, Fujitani S, Yoshida S, Matsumoto H, et al. Quantitative verification of the effect of using an umami substance (l-glutamate) to reduce salt intake. Hypertens Res. 2020;43(6):579–581.

    Article  Google Scholar 

  3. 3.

    Hayabuchi H, Morita R, Ohta M, Nanri A, Matsumoto H, Fujitani S, et al. Validation of preferred salt concentration in soup based on a randomized blinded experiment in multiple regions in Japan-influence of umami (l-glutamate) on saltiness and palatability of low-salt solutions. Hypertens Res. 2020;43(6):525–533.

    CAS  Article  Google Scholar 

  4. 4.

    Bannai M, Torii K. Digestive physiology of the pig symposium: detection of dietary glutamate via gut–brain axis. J Anim Sci. 2013;91(5):1974–1981.

    CAS  Article  Google Scholar 

  5. 5.

    Satoh-Kuriwada S, Kawai M, Iikubo M, Sekine-Hayakawa Y, Shoji N, Uneyama H, et al. Development of an umami taste sensitivity test and its clinical use. PLoS ONE. 2014;9(4):e95177.

    Article  Google Scholar 

  6. 6.

    Pepino MY, Finkbeiner S, Beauchamp GK, Mennella JA. Obese women have lower monosodium glutamate taste sensitivity and prefer higher concentrations than do normal-weight women. Obesity. 2010;18(5):959–965.

    Article  Google Scholar 

  7. 7.

    Mizuta E, Kokubo Y, Yamanaka I, Miyamoto Y, Okayama A, Yoshimasa Y, et al. Leptin gene and leptin receptor gene polymorphisms are associated with sweet preference and obesity. Hypertens Res. 2008;31(6):1069–1077.

    CAS  Article  Google Scholar 

  8. 8.

    McLean RM, Farmer VL, Nettleton A, Cameron CM, Cook NR, Woodward M, et al. Twenty-Four-Hour Diet recall and Diet records compared with 24-hour urinary excretion to predict an individual’s sodium consumption: a systematic review. J Clin Hypertens. 2018;20(10):1360–1376.

    Article  Google Scholar 

  9. 9.

    Tanaka T, Okamura T, Miura K, Kadowaki T, Ueshima H, Nakagawa H, et al. A simple method to estimate populational 24-h urinary sodium and potassium excretion using a casual urine specimen. J Hum Hypertens. 2002;16(2):97–103.

    CAS  Article  Google Scholar 

  10. 10.

    Shim J, Son HJ, Kim Y, Kim KH, Kim JT, Moon H, et al. Modulation of sweet taste by umami compounds via sweet taste receptor subunit hT1R2. PLoS ONE. 2015;10(4):e0124030.

    Article  Google Scholar 

Download references

Author information



Corresponding author

Correspondence to Einosuke Mizuta.

Ethics declarations

Conflict of interest

The author EM has no conflicts of interest. The coauthor, IH, has received lecture and/or manuscript fees from Sanwa Kagaku Kenkyusho Co., Ltd., Teijin Pharma, Ltd., Mochida Pharmaceutical Co., Ltd., and Fujiyakuhin Co., Ltd. The other coauthors declare that they have no conflicts of interest.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Mizuta, E., Kinugasa, Y., Kato, M. et al. Umami taste disorder is a novel predictor of obesity. Hypertens Res 44, 595–597 (2021).

Download citation


Quick links