Table 1 Descriptive characteristics of the entire cohort (N = 1812)d.

From: Diagnosing hereditary cancer predisposition in men with prostate cancer

  Total (N) Total (%)
Age at testing (IQR) 66 (59,73)  
Race/ethnicity
  African American/Black 109 6.0%
  Ashkenazi Jewish 165 9.1%
  Asian 23 1.3%
  Caucasian 1268 70.0%
  Hispanic 47 2.6%
  Middle Eastern 7 0.4%
  Mixed ethnicity 65 3.6%
  Native American 2 0.1%
  Other 8 0.4%
  Unknown 118 6.5%
Personal history of other cancersa
  Yes 758 41.8%
  No 1054 58.2%
Personal history of other cancersc
  Breast 105 5.8%
  Colorectal 201 11.1%
  Pancreatic 111 6.1%
  Other 487 26.9%
  None 1054 58.2%
Family history of cancerb,c
  Yes 1674 92.4%
  No 138 7.6%
Family history of cancer
  Breast 943 52.0%
  Colorectal 578 31.9%
  Pancreatic 313 17.3%
  Prostate 917 50.6%
  Other 1177 65.0%
Gleason score
  Low (<7) 162 17.7%
  Intermediate (7) 396 43.2%
  High (8–10) 359 39.1%
  Missing 895  
>1 Family member with breast, ovarian, or pancreatic cancer
  Yes 649 35.8%
  No 1163 64.2%
>1 Family member with Lynch syndrome–related cancer
  Yes 572 31.6%
  No 1240 68.4%
Test ordered
  ProstateNext 284 15.7%
  Other multigene panel tests 1528 84.3%
  1. aCancer status “not provided” and “no” are treated as the same.
  2. bOnly first-, second-, and third-degree relatives are included.
  3. cNonmelanoma skin cancers and unspecified cancers are excluded.
  4. dExcluded 66 probands with a known BRCA1/2 pathogenic variant in the family.