ADDENDUM: Genetic counseling and testing for Alzheimer disease: joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors

Addendum to: Genetics in Medicine 13: 597–605 (2011); https://doi.org/10.1097/GIM.0b013e31821d69b8, published online 16 May 2011

This document was reaffirmed by the ACMG Board of Directors as of 25 June 2018 with the following addendum:

We suggest the following considerations in reaffirming this document:

  1. 1.

    To use the phrase “pathogenic variant” rather than the word “mutation” in discussing pathogenic variants related to autosomal dominant early-onset Alzheimer disease. This would be consistent with current ACMG/AMP Guidelines for Variant Interpretation and Reporting1.

  2. 2.

    Because this document no longer meets the criteria for an evidence-based practice guideline by either the American College of Medical Genetics and Genomics (ACMG) or National Society of Genetic Counselors (NSGC), NSGC reclassified this document as a Practice Resource in 2016, and ACMG is also classifying it as a Practice Resource as of this reaffirmation.

Correspondence: acmg@acmg.net

Reference

  1. 1.

    Richards S, Aziz N, Bale, S, et al. Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. Genet Med. 2015;17:405–423. https://www.nature.com/articles/gim201530. Accessed 14 June 2019.

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Jill S. Goldman MS, MPhil.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Goldman, J.S., Hahn, S.E., Catania, J.W. et al. ADDENDUM: Genetic counseling and testing for Alzheimer disease: joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors. Genet Med 21, 2404 (2019). https://doi.org/10.1038/s41436-019-0559-1

Download citation