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Comment on: Vitrectomy in Small idiopathic MAcuLar hoLe (SMALL) study: conventional internal limiting membrane peeling versus inverted flap

Eye (2024)Cite this article

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We read with great interest the recent article titled “Vitrectomy in Small Idiopathic Macular Hole (SMALL) Study: Conventional Internal Limiting Membrane Peeling versus Inverted Flap,” published in Eye by Matteo Fallico et al. [1].

Notably, the inverted flap technique seems to offer no significant advantages over conventional ILM peeling. This finding challenges the growing trend of adopting more complex techniques without clear evidence of their benefits.

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References

  1. Fallico, M, Caselgrandi, P, Marolo, P, Parisi G, Borrelli E, Ricardi F, et al. Vitrectomy in Small idiopathic MAcuLar hoLe (SMALL) study: conventional internal limiting membrane peeling versus inverted flap. Eye. 2024. https://doi.org/10.1038/s41433-024-03301-z

  2. Spiteri Cornish K, Lois N, Scott N, Burr J, Cook J, Boachie C, et al. Vitrectomy with internal limiting membrane (ILM) peeling versus vitrectomy with no peeling for idiopathic full-thickness macular hole (FTMH). Cochrane Database Syst Rev. 2013:CD009306. https://doi.org/10.1002/14651858.CD009306.pub2.

  3. Michalewska Z, Michalewski J, Adelman RA, Nawrocki J. Inverted internal limiting membrane flap technique for large macular holes. Ophthalmology. 2010;117:2018–25.

    Article  PubMed  Google Scholar 

  4. Ch’ng SW, Patton N, Ahmed M, Ivanova T, Baumann C, Charles S, et al. The Manchester Large Macular Hole Study: Is it time to reclassify large macular holes? Am J Ophthalmol. 2018;195:36–42.

    Article  PubMed  Google Scholar 

  5. Mete M, Alfano A, Guerriero M, Prigione G, Sartore M, Polito A, et al. Inverted internal limiting membrane flap technique versus complete internal limiting membrane removal in myopic macular hole surgery: a comparative study. Retina. 2017;37:1923–30.

    Article  PubMed  Google Scholar 

  6. Faria MY, Proenca H, Ferreira NG, Sousa DC, Neto E, Marques-Neves C. Inverted internal limiting membrane flap techniques and outer retinal layer structures. Retina. 2020;40:1299–305.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Ophthalmology Unit, Dipartimento di Scienze Mediche e Chirurgiche, Alma Mater Studiorum, University of Bologna, Bologna, Italy

    Maurizio Mete, Alessandro Finzi, Antonio Moramarco & Luigi Fontana

  2. IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy

    Maurizio Mete, Alessandro Finzi, Antonio Moramarco & Luigi Fontana

Authors
  1. Maurizio Mete
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  2. Alessandro Finzi
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  3. Antonio Moramarco
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  4. Luigi Fontana
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MM wrote the letter. AF, AM, and LF provided feedback on the letter.

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Correspondence to Maurizio Mete.

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Mete, M., Finzi, A., Moramarco, A. et al. Comment on: Vitrectomy in Small idiopathic MAcuLar hoLe (SMALL) study: conventional internal limiting membrane peeling versus inverted flap. Eye (2024). https://doi.org/10.1038/s41433-024-03376-8

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  • DOI: https://doi.org/10.1038/s41433-024-03376-8

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