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The potential influence of sleep on translaminar pressure dynamics and ocular glymphatic outflow in microgravity: implications for optic disc edema in astronauts

Eye (2024)Cite this article

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Dear Editor,

We read with great interest and enthusiasm the article by Nguyen et al. [1]. We greatly appreciate the tremendous contributions Prof. Lee and his team have made to our understanding of spaceflight associated neuro-ocular syndrome (SANS), and we are grateful to the authors for sharing their new work with the scientific community.

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References

  1. Nguyen T, Ong J, Waisberg E, Lee AG. Sleep and optic disc edema in spaceflight associated neuro-ocular syndrome (SANS). Eye (Lond). 2024. https://doi.org/10.1038/s41433-024-03119-9.

  2. Christian KH, Petitti C, Ortega-Schwartz K, Mulder E, Noppe A, von der Wiesche M, et al. Development of optic disc edema during 30 days of hypercapnic head down tilt bed rest is associated with short sleep duration and blunted temperature amplitude. J Appl Physiol (1985). 2024;136:753–63.

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Authors and Affiliations

  1. Department of Psychiatry, PC Sint-Amandus, Beernem, Belgium

    Peter Wostyn

  2. Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

    Maiken Nedergaard

  3. Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY, USA

    Maiken Nedergaard

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  1. Peter Wostyn
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  2. Maiken Nedergaard
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PW drafted and wrote the manuscript. MN commented and revised the intellectual content of the manuscript. All authors have read and approved the final version of the manuscript.

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Correspondence to Peter Wostyn.

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Wostyn, P., Nedergaard, M. The potential influence of sleep on translaminar pressure dynamics and ocular glymphatic outflow in microgravity: implications for optic disc edema in astronauts. Eye (2024). https://doi.org/10.1038/s41433-024-03269-w

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