Keratopigmentation: a comprehensive review


Corneal keratopigmentation (KTP) has a long history of use in management of patients suffering from disfiguring corneal opacities. Due to progresses and modifications in KTP surgical techniques and its low rate of complications, it is taken into consideration to be used in selected groups of patients for therapeutic or functional indications. In this paper we present an overview on clinical applications of KTP in both cosmetic and functional aspects and also, we discuss the outcomes of KTP and its characteristics in experimental and histopathological studies.


角膜墨染术 (Corneal keratopigmentation KTP) 在治疗角膜混浊的患者有着悠久的历史。由于KTP手术技术的更新与改进以及其并发症的低发生率, 因此通常被考虑用于治疗性或功能性适应症的患者。本文阐述了KTP在美容和功能方面的临床应用, 并讨论了KTP的手术效果及其在实验和组织病理学研究中的特点。

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Fig. 1: Illustrations of different methods of keratopigmentations (KTP).
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We acknowledge Dr Alio and his colleagues because of their great work in developing the novel system of keratopigmentation. Also, we would like thank Danial Alebouyeh for his contribution in designing the illustrations used in this paper.

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Correspondence to Acieh Es’haghi.

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Hasani, H., Es’haghi, A., Rafatnia, S. et al. Keratopigmentation: a comprehensive review. Eye 34, 1039–1046 (2020).

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