Table 5 Hazard ratios of progression in RNFL thinning on OCT scans by using multivariate Cox proportional hazards regression model

From: Correlation between structural progression in glaucoma and obstructive sleep apnea

 Hazard ratio (95% CI)P value
Age at diagnosis (>65 years)0.965 (0.123–7.582)0.973
Sex (Female)0.684 (0.067–6.975)0.748
DM2.441 (0.337–17.692)0.377
Hypertension0.231 (0.063–0.852)0.028
Hyperlipidemia0.799 (0.163–3.912)0.781
Pre-obese (23.0 ≤ BMI < 27.5)27617.670 (0.000–3.24E158)0.955
Obese (BMI ≥ 27.5)12913.430 (0.000–1.52E158)0.958
Mild OSA (5 ≤ AHI < 15)0.500 (0.027–9.204)0.641
Moderate OSA (15 ≤ AHI < 30)1.996 (0.377–10.577)0.416
Severe OSA (AHI ≥ 30)8.448 (1.464–48.752)0.017
  1. Model adjusted for age, sex, DM, hypertension, hyperlipidemia, and BMI
  2. RNFL retinal nerve fiber layer, OCT optical coherence tomography, DM diabetes mellitus, BMI body mass index, OSA obstructive sleep apnea, AHI apnea–hypopnea index