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Torn from the headlines: role of public awareness and bench- to-bedside research in prevention and treatment of Acanthamoeba keratitis

Eyevolume 33pages698701 (2019) | Download Citation

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References

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    Carnt N PhD, Hoffman JJ MBBS, Verma S, Hau S, Radford CF PhD, Minassian DC, et al. Acanthamoeba keratitis: confirmation of the UK outbreak and a prospective case-control study identifying contributing risk factors. Br J Ophthalmol. 2018;102:1621–1628. Epub 2018 Sep 19. PubMed PMID: 30232172. https://www.ncbi.nlm.nih.gov/pubmed/30232172.

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    Lalitha P, Lin CC, Srinivasan M, Mascarenhas J, Prajna NV, Keenan JD, et al. Acanthamoeba keratitis in South India: a longitudinal analysis of epidemics. Ophthalmic Epidemiol. 2012;19:111–5.

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    Baig AM, Waliani N, Karim S. Drug target discovery methods in targeting neurotropic parasitic amoebae. ACS Chem Neurosci. 2018;9:162–4.

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    Baig AM, Rana Z, Tariq S, Lalani S, Ahmad HR. Traced on the timeline: discovery of acetylcholine and the components of the human cholinergic system in a primitive unicellular eukaryote Acanthamoeba spp. ACS Chem Neurosci. 2018;;9:494–504. https://doi.org/10.1021/acschemneuro.7b00254.

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    J Gueudry, R Razakandrainibe, C Humbert, A Aifa, A Francois, LLe Goff, et al. Orphan drug for Acanthamoeba keratitis (ODAK) project: validation of an Acanthamoeba polyphaga keratitis model. Acta Ophthalmologica. 2014; 92: SN. 1755-375X; https://doi.org/10.1111/j.1755-3768.2014. 4421.x.

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Funding and Acknowledgment

This project has been partly funded by Aga Khan University, Pakistan. Author would like to thank Miss Preet Katyara for critical review and helpful discussions.

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  1. The Aga Khan University, Karachi, Pakistan

    • Abdul Mannan Baig

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The authors declare that they have no conflict of interest.

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Correspondence to Abdul Mannan Baig.

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https://doi.org/10.1038/s41433-018-0306-x