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Oral health

Is there an association between oral hygiene and head and neck cancer?

Evidence-Based Dentistry volume 24, pages 57–58 (2023)Cite this article

Subjects

Abstract

Data sources

PubMed, Web of Science, the Cochrane Library and Embase were utilised as databases from inception till November 2021.

Study selection

The inclusion criteria consisted of cohort and case-control studies published in the English language, which dealt with diagnosed cases of head and neck cancer reporting survival, oral hygiene and comparative data. Studies pertaining to animal experiments along with case reports, conference proceedings, reviews, letters, editorials, errata and protocols were excluded.

Data extraction and synthesis

Data such as publication year, authors’ names, country, sources, study groups, age, gender, participant number, education, alcohol, tobacco, study quality, cancer site and outcomes were extracted for each included study. A modified Newcastle-Ottawa Scale was utilized to evaluate the quality of these studies.

Results

A total of forty-four studies were included, of which forty were case-control and four were cohort in nature. These comprised of a total of 52,863 patients of which 33,000 were devoid of head and neck cancer (HNC) while, 19,863 had a confirmed diagnosis of HNC. Oral hygiene and HNC were found to be associated.

Conclusions

Poor oral hygiene was concluded to be associated with HNC and the subsites thereof.

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References

  1. Chang CC, Lee WT, Hsiao JR, Ou CY, Huang CC, Tsai ST, et al. Oral hygiene and the overall survival of head and neck cancer patients. Cancer Med. 2019;8:1854–64. https://doi.org/10.1002/cam4.2059.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Hashim D, Sartori S, Brennan P, Curado MP, Wünsch-Filho V, Divaris K, et al. The role of oral hygiene in head and neck cancer: results from International Head and Neck Cancer Epidemiology (INHANCE) consortium. Ann Oncol. 2016;27:1619–25. https://doi.org/10.1093/annonc/mdw224.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Karpiński TM. Role of oral microbiota in cancer development. Microorganisms. 2019;7:20. https://doi.org/10.3390/microorganisms7010020.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Eliot MN, Michaud DS, Langevin SM, McClean MD, Kelsey KT. Periodontal disease and mouthwash use are risk factors for head and neck squamous cell carcinoma. Cancer Causes Control. 2013;24:1315–22. https://doi.org/10.1007/s10552-013-0209-x.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Langevin SM, Michaud DS, Eliot M, Peters ES, McClean MD, Kelsey KT. Regular dental visits are associated with earlier stage at diagnosis for oral and pharyngeal cancer. Cancer Causes Control. 2012;23:1821–9. https://doi.org/10.1007/s10552-012-0061-4.

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Infectious Disease and Immunology, The Forsyth Institute, Cambridge, MA, 02142, USA

    Vaibhav Sahni

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  1. Vaibhav Sahni
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Correspondence to Vaibhav Sahni.

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The author declares no competing interests.

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Cite this article

Sahni, V. Is there an association between oral hygiene and head and neck cancer?. Evid Based Dent 24, 57–58 (2023). https://doi.org/10.1038/s41432-023-00879-3

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  • DOI: https://doi.org/10.1038/s41432-023-00879-3

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