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Contributing to the on-going debate around the clinical application of preimplantation embryo selection based on polygenic risk scores (PGT-P)

European Journal of Human Genetics volume 31, pages 1099–1100 (2023)Cite this article

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The article by Siermann et al. [1] in this issue presents the findings of a questionnaire-based survey of 31 health care professionals (HCPs) involved in Preimplantation Genetic Testing (PGT), representing one of the main groups of stakeholders potentially involved in the routine application of PGT-P. The questionnaires took the form of interviews performed over a 6-month period, and the results reported in this article cover the HCPs’ views relating to the potential validity of the PGT-P technology, the clinical utility, the limitations and consequences of using PGT-P, as well as potential benefits.

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References

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Authors and Affiliations

  1. Laboratory of Medical Genetics, National and Kapodistrian Univeristy of Athens, St. Sophia’s Children’s Hospital, Athens, Greece

    Periklis Makrythanasis, Georgia Kakourou, Thalia Mamas, Christina Vrettou & Jan Traeger-Synodinos

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  1. Periklis Makrythanasis
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  2. Georgia Kakourou
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  3. Thalia Mamas
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  4. Christina Vrettou
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  5. Jan Traeger-Synodinos
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Contributions

PM, GK and JTS wrote the manuscript; TM and CV provided feedback and editing.

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Correspondence to Jan Traeger-Synodinos.

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The authors declare no competing interests.

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Makrythanasis, P., Kakourou, G., Mamas, T. et al. Contributing to the on-going debate around the clinical application of preimplantation embryo selection based on polygenic risk scores (PGT-P). Eur J Hum Genet 31, 1099–1100 (2023). https://doi.org/10.1038/s41431-023-01372-2

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  • DOI: https://doi.org/10.1038/s41431-023-01372-2

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