Table 4 Predicted uptake of the four testing alternatives in current practice

From: Do health professionals value genomic testing? A discrete choice experiment in inherited cardiovascular disease

Test Test attributes and levels Utility score Probability of uptake
Pathogenic mutation identified in X out of every 100 cases VUS identified in X out of every 100 cases Cost Counselling Secondary findings disclosed Mean SD Mean SD
WGS 50 55 £5000 60 min Subset −18.5 30.8 0.10% 0.60%
WES 45 35 £2500 60 min Subset 9.0 15.2 1.40% 4.10%
Panel 40 15 £300 30 min None 33.9 15.9 98.10% 6.20%
None 0 0 £0 0 min None −0.1 0.0 0.40% 2.30%
  1. Panel panel test, SD standard deviation, VUS variants of unknown significance, WES whole exome sequencing, WGS whole genome sequencing