Fig. 1 | European Journal of Human Genetics

Fig. 1

From: Haploinsufficiency of ARHGAP42 is associated with hypertension

Fig. 1

a Pedigree of the family with the proband (III.5, indicated with an arrow), her mother (II.2), two brothers (III.2 and III.4), niece (IV.4) and nephew (IV.3) carrying a t(11;18) reciprocal translocation. Individuals with normal karyotypes are indicated in grey, whereas individuals not analysed are indicated in white. Phenotypes are as annotated with hypertension indicated by a white dot and body mass index (BMI) written below. Underneath each translocation carrier, except individuals IV.3 and IV.4, who were unavailable for investigation, the SNP haplotypes from Sanger sequencing of genomic DNA are shown. b Partial karyogram of the t(11;18)(q22.1;q12.2) translocation, showing the normal and derivative (der) chromosomes 11 and 18. The approximate breakpoint positions are indicated by arrows

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