Abstract
Background and Objectives
Body composition (BC) assessment in cirrhosis has a wide variety of methods with no consensus on the best tools for each body component in patients with Liver Cirrhosis (LC). We aimed to conduct a systematic scoping review of the most frequent body composition analysis methods and nutritional findings published in liver cirrhosis patients.
Methods
We searched for articles in PubMed, Scopus, and ISI Web of Science databases. Keywords selected the BC methods and parameters in LC.
Results
Eleven methods were found. The most frequently used were computed tomography (CT) 47.5%, Bioimpedance Analysis 35%, DXA 32.5%, and anthropometry 32.5%. Up to 15 BC parameters were reported from each method.
Conclusions
The vast heterogeneity in the results found during the qualitative analysis and imaging methods must reach a consensus to achieve a better clinical practice and improve nutritional treatment, as the physiopathology in LC compromises the nutritional status directly.
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Data availability
The data generated and analysed during this study can be found within the published article as a Supplementary Online-only file.
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Acknowledgements
AJEF was a research fellow at the Directorate of Research in HGMEL during 2020–2022. AJEF was supported by the Consejo Nacional de Ciencia y Tecnologia (CONACyT), Mexico fellowship award. This work was submitted in partial fulfilment of the requirements for the MSc degree of AJEF at the Programa de Maestria en Ciencias de la Salud, Escuela Superior de Medicina, Instituto Politecnico Nacional, Mexico. This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.
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Conceptualisation, AJEF, EGO, and ERV; methodology, AJEF, EGO, and ERV; software AJEF, EGO and ERV; Validation, AJEF, EGO, NBH, ERV, GMM, and SKT; formal analysis, AJEF, EGO, NBH, ERV, GMM, and SKT; investigation, AJEF, and EGO; resources, ERV; data curation AJEF and EGO; writing—original draft preparation, AJEF, EGO, NBH, ERV, GMM, and SKT; writing—review and editing, AJEF, EGO, NBH, ERV, GMM, and SKT; visualisation, AJEF, EGO, NBH, ERV, GMM, and SKT; supervision, ERV; project administration, ERV; funding acquisition, NA. All authors have read and agreed to the published version of the manuscript.
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Espinosa-Flores, AJ., Guzman-Ortiz, E., Melendez-Mier, G. et al. A scoping review of the methods used in patients with liver cirrhosis to assess body composition and their nutritional findings. Eur J Clin Nutr 77, 845–854 (2023). https://doi.org/10.1038/s41430-023-01287-7
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DOI: https://doi.org/10.1038/s41430-023-01287-7