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Comments on “The effects of chromium supplementation on blood pressure: a systematic review and meta-analysis of randomized clinical trials”

European Journal of Clinical Nutrition volume 77, page 506 (2023)Cite this article

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We read the recent report in EJCN Journal with great interest by Ghanbari et al. [1], which is entitled “The effects of chromium supplementation on blood pressure: a systematic review and meta-analysis of randomized clinical trials”. Some methodological limitations in the article that may nullify the conclusion need to be mentioned. Firstly, the authors mentioned that they had searched PubMed, SCOPUS, Cochrane Library, Web of Science, and Embase; however, they failed to include one relevant study [2]. Secondly, the authors should consider the within-person correlation between active and placebo outcomes conditions of crossover studies [3, 4] or analyze only the studies with parallel-group. Finally, according to the Cochrane handbook, entering multiple comparisons from one study [5, 6] overestimates the effect size and creates a unit-of-analysis error. We want to congratulate the authors on their findings and hope that our improvement will add to the credibility of conclusions reported in this meta-analysis.

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References

  1. Ghanbari M, Amini MR, Djafarian K, Shab-Bidar S. The effects of chromium supplementation on blood pressure: a systematic review and meta-analysis of randomized clinical trials. Eur J Clin Nutr. 2021. https://doi.org/10.1038/s41430-021-00973-8.

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Authors and Affiliations

  1. Department of Physiology and Iranian Medicine, School of Medicine, AJA University of Medical Sciences, Tehran, Iran

    Sayid Mahdi Mirghazanfari

  2. Trauma Research Center, AJA University of Medical Sciences, Tehran, Iran

    Ebrahim Hazrati

  3. Department of Nutrition, School of Medicine, AJA University of Medical Sciences, Tehran, Iran

    Vahid Hadi & Saeid Hadi

  4. Department of Military Nursing, Faculty of Nursing, AJA University of Medical Sciences, Tehran, Iran

    Faeze Bani Yaghoobi

  5. Department of Management and Health Economy, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran

    Morad Esmaeil Zali

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  1. Sayid Mahdi Mirghazanfari
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Contributions

SMM, EH, VH, FBY, MEZ, and SH was responsible for designing and writing the letter. All authors read and approved the final manuscript.

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Correspondence to Saeid Hadi.

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Mirghazanfari, S.M., Hazrati, E., Hadi, V. et al. Comments on “The effects of chromium supplementation on blood pressure: a systematic review and meta-analysis of randomized clinical trials”. Eur J Clin Nutr 77, 506 (2023). https://doi.org/10.1038/s41430-022-01235-x

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