Fig. 4: Mitopure supplementation delivers significantly higher plasma UA levels compared to PJ. | European Journal of Clinical Nutrition

Fig. 4: Mitopure supplementation delivers significantly higher plasma UA levels compared to PJ.

From: Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population

Fig. 4

Pharmacokinetic profiles at T0, T6 (6 h), and T24 (24 h) and mean absolute change in levels from T0 to T24 (primary outcome of study) between the two interventions of PJ and Mitopure supplementation for UA glucuronide (A, B), UA sulfate (C, D), and parent UA (E, F) showing significantly higher plasma levels of UA and its metabolites with Mitopure supplementation compared to PJ dietary challenge (N = 100). All data are analyzed using a repeated measure ANOVA (A, C, E) and an unpaired t-test (B, D, F).

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