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Nutrition in acute and chronic diseases

Evaluation of nutritional status in COPD according to the GOLD-2015 staging system: a prospective observational study

European Journal of Clinical Nutrition volume 74, pages 1354–1361 (2020)Cite this article

Subjects

Abstract

Objectives

This study aimed to assess nutritional statuses of chronic obstructive pulmonary disease (COPD) patients in four categories of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2015 classification and to evaluate associations of body mass index (BMI) and fat-free mass index with respiratory and skeletal muscle strengths.

Methods

This prospective observational study included COPD patients (≥40 years old) who were followed-up for at least 1 year. Medical histories, smoking status, and anthropometric, spirometry, and hand grip strength measurements were recorded.

Results

This study included 463 COPD patients. They were classified as Group A (n = 119), Group B (n = 58), Group C (n = 117), and Group D (n = 169) according to GOLD. Group D was older (p = 0.001) than other groups. No difference was found among the groups regarding sex (p = 0.163). Fat-free body mass was significantly decreased in Group D compared with Group A (p = 0.014) and BMI were lower in Groups C and D than in other groups (p = 0.001). Spirometry and hand grip strength showed a significant decreasing trend toward Group D (p < 0.001 for both).

Conclusions

Patients with COPD in advanced-stages had decreased BMI, fat-free body mass, hand grip strength, and respiratory and skeletal muscle functions. Nutritional status should be routinely monitored and considered an important indicator in COPD.

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Data availability

The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

We thank Dr Muyesser Ertugrul for her helps in the study design.

Funding

The study was funded by Nutricia Advanced Medical Nutrition Turkey, Medical Affairs Department.

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Authors and Affiliations

  1. Department of Chest Diseases, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey

    Sibel Arinc, Meltem Agca & Feride Yaman

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  1. Sibel Arinc
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Contributions

SA has made substantial contributions to design of the work and has drafted the work and substantively revised it; and read and approved the final paper. MA has made substantial contributions to the acquisition, analysis, and interpretation of data and read and approved the final paper. FY has made substantial contributions to the acquisition, analysis, and interpretation of data and read and approved the final paper.

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Correspondence to Sibel Arinc.

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Arinc, S., Agca, M. & Yaman, F. Evaluation of nutritional status in COPD according to the GOLD-2015 staging system: a prospective observational study. Eur J Clin Nutr 74, 1354–1361 (2020). https://doi.org/10.1038/s41430-020-0663-y

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