Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

(Dis) Agreement between the first and the recent European consensus on definition and diagnosis for sarcopenia in kidney transplant patients

Abstract

We previously detected that ~50% of kidney transplant patients (KTPs) present sarcopenia using the first European Working Group on Sarcopenia in Older People (EWGSOP1) consensus. Our aim was to evaluate the agreement between the sarcopenia diagnosis using EWGSOP1 and the new consensus (EWGSOP2) in KTPs. A cross-sectional study was performed evaluating 127 KTPs. Total and appendicular muscle mass were estimated by bioelectrical impedance. Strength was evaluated by handgrip strength (HGS) and five times sit to stand (5STS). Functional capacity was evaluated by 4-m walk test and short physical performance battery. Sarcopenia was diagnosed by EWGSOP1 and EWGSOP2. The agreement between EWGSOP1 and EWGSOP2 (using HGS criteria for muscle strength) was fair (k = 0.341–0.402). Slight agreement was observed between EWGSOP1 and EWGSOP2 using 5STS criteria for muscle strength (k = 0.031–0.046). We conclude that EWGSOP2 definitions have a low agreement with EWGSOP1 in KTPs.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

References

  1. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al. Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412–23.

    Article  Google Scholar 

  2. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyere O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48:16–31.

    Article  Google Scholar 

  3. Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopeniaI in older persons is associated with functional impairmente and physical disability. Am Geriatr Soc. 2002;50:889–96.

  4. Sergi G, De Rui M, Veronese N, Bolzetta F, Berton L, Carraro S, et al. Assessing appendicular skeletal muscle mass with bioelectrical impedance analysis in free-living Caucasian older adults. Clin Nutr. 2015;34:667–73.

    Article  Google Scholar 

  5. dos Reis AS, Santos HO, Limirio LS, de Oliveira EP. Phase angle is associated with handgrip strength but not with sarcopenia in kidney transplantation patients. J Ren Nutr. 2019;29:196–204.

    Article  Google Scholar 

  6. Lohman TG. Anthropometric standardization reference manual. Champaign, IL: Human Kinetics; 1998.

  7. Matsudo SM, Matsudo VR, Araújo T. et al. Nível de atividade física da população do estado de São Paulo, análise de acordo com o gênero, idade, nível socioeconômico, distribuição geográfica e de conhecimento. Rev Bras Ciênc Mov. 2002;10:41–50.

    Google Scholar 

  8. Reis BCA, de Branco FMS, Pessoa DF, Barbosa CD, dos Reis AS, de Medeiros LA, et al. Phase angle is positively associated with handgrip strength in hospitalized individuals. Top Clin Nutr. 2018;33:127–33.

    Article  Google Scholar 

  9. Janssen I, Heymsfield SB, Baumgartner RN, Ross R. Estimation of skeletal muscle mass by bioelectrical impedance analysis. J Appl Physiol. 2000;89:465–71.

    Article  CAS  Google Scholar 

  10. de Branco FMS, Carneiro MAS, Rossato LT, Nahas PC, Teixeira KRC, de Oliveira GN, Jr. et al. Protein timing has no effect on lean mass, strength and functional capacity gains induced by resistance exercise in postmenopausal women: a randomized clinical trial. Clin Nutr. 2019. https://doi.org/10.1016/j.clnu.2019.01.008.

  11. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyere O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48:601.

    Article  Google Scholar 

  12. Sim J, Wright CC. The kappa statistic in reliability studies: use, interpretation, and sample size requirements. Phys Ther. 2005;85:257–68.

    Article  Google Scholar 

Download references

Acknowledgements

We are thankful for the patients that participated of this study.

Author information

Authors and Affiliations

Authors

Contributions

LSL and HOS wrote the manuscript and participated in collection and analysis of data; ASR participated in collection and analysis of data; and EPO carried out the conception and design of the study, participated in the interpretation of the data, wrote, and contributed to the revision of the manuscript.

Corresponding author

Correspondence to Erick P. de Oliveira.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary information

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Limirio, L.S., Santos, H.O., dos Reis, A.S. et al. (Dis) Agreement between the first and the recent European consensus on definition and diagnosis for sarcopenia in kidney transplant patients. Eur J Clin Nutr 74, 1104–1108 (2020). https://doi.org/10.1038/s41430-019-0535-5

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41430-019-0535-5

This article is cited by

Search

Quick links