The use of raw bioelectrical variables, such as resistance (R), reactance (Xc), and phase angle (φ), has been advocated for evaluating physiological changes.
Before and after 8 weeks of resistance training, adult females were assessed via multifrequency bioelectrical impedance analysis (MFBIA; Seca® mBCA 515/514) and bioimpedance spectroscopy (BIS; ImpediMed® SFB7). Data were analyzed to determine whether cross-sectional estimates and changes (i.e., Δ scores) of R, Xc, and φ differed between devices at 16 shared measurement frequencies ranging from 3 to 1000 kHz.
Cross-sectionally, strong correlations (r ≥ 0.96) were observed for R across all frequencies, although MFBIA produced values 9–14% greater than BIS. Strong correlations (r ≥ 0.92) for Xc and φ were observed up to frequencies of ~150 kHz. BIS produced greater Xc and φ values at lower frequencies, while MFBIA produced greater values at higher frequencies. In general, proportional bias was not observed, with the exception of Xc at high frequencies and φ at low frequencies. ΔR did not differ between devices at any frequency and was correlated at all frequencies. ΔXc and Δφ did not differ at any frequency and were correlated between devices for frequencies up to ~300 kHz. Proportional bias was generally not observed longitudinally. While individual-level errors were potentially acceptable cross-sectionally, they were concerningly high longitudinally.
Despite notable differences in the characteristics of the bioimpedance devices and cross-sectional disagreement, strong group-level agreement for detecting changes in R, Xc, and φ was generally observed. However, large errors were observed at the individual level.
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The authors would like to acknowledge Austin Graybeal, Jacob Dellinger, and Robert Smith for their contributions to this project.
The original project yielding the data used in this analysis was financially supported by Texas Tech University and MTI Biotech Inc. In-kind donations to support the original data collection were received from Dymatize Enterprises and MTI Biotech Inc. These entities did not play a role in the overall design or execution of the study, the analysis and interpretation of the data, or the presentation of the results found in this manuscript.
Conflict of interest
The authors declare that they have no conflict of interest.
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