Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Body composition, energy expenditure and physical activity

Intrauterine growth restriction and overweight, obesity, and stunting in adolescents of indigenous communities of Chiapas, Mexico

Abstract

Background/objectives

Intrauterine growth restriction (IUGR) and low-birth-weight (LBW) are determinant factors in the development of metabolic diseases in children and adolescents. To estimate the magnitude of the association between LBW and IUGR with stunting or obesity among adolescents of two indigenous regions of the southern State of Chiapas, Mexico.

Subjects/methods

We assessed a random sample of 303 adolescents selected from a birth cohort study (2003) conducted in three hospitals serving urban and rural communities of Tzotzil-Tzeltal and Selva regions of Chiapas, Mexico. Sociodemographic and anthropometric data from a sample of adolescents were correlated with their anthropometric data at birth (weight, length for age). Logistic regression models were fitted to estimate odds ratios (OR) with 95% confidence intervals to measure the magnitude of the association among the variables of interest. Models were adjusted for potential confounders.

Results

In all, 12% of the sample had LBW and 28.8% IUGR. In total, 29% of adolescents were overweight/obese and 21% were stunted. We found a statistically significant association between IUGR and a lower risk of being overweight/obese. A higher probability for stunting was observed for LBW and IUGR.

Conclusions

Stunting and overweight/obesity prevalence in this population of adolescents was high and was associated with IUGR.

This is a preview of subscription content

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Fig. 1

References

  1. 1.

    Rohrer F. Der index der korperpirlle als Mass des Ernahrungszustandes (Index of state of nutrition). Munch Med Wochenschr. 1921;68:580–2.

    Google Scholar 

  2. 2.

    Casanello P, Castro-Rodríguez JA, Uauy R, Krause BJ. Programación epigenética placentaria en restricción del crecimiento intrauterino. Rev Chil Pediatr. 2016;87:154–61.

    Article  Google Scholar 

  3. 3.

    Barker D, Eriksson J, Forsen T, Osmond C. Fetal origins of adult disease: strength of effects and biological basis. Int J Epidemiol. 2002;31:1235–9.

    CAS  Article  Google Scholar 

  4. 4.

    Valladares-Salgado A, Suárez-Sánchez F, Burguete-García AI, Cruz M. Temas de actualidad Epigenética de la obesidad infantil y de la diabetes. Rev Med Inst Mex Seguro Soc. 2014;52:88–93.

    Google Scholar 

  5. 5.

    Rojo-Trejo M, Rangel Peniche D, Arellano Jimenez M, Sabath Silva E. Composición corporal de niños de entre 8 y 10 años de edad, con y sin antecedente de bajo peso al nacer, residentes en el estado de Querétaro, México. Nutr Hosp. 2016;33:544–8.

    Article  Google Scholar 

  6. 6.

    Domínguez Hernández C, Klünder M, Huang F, Flores Armas E, Velázquez-López L, Medina-Bravo P. Association between abdominal fat distribution, adipocytokines and metabolic alterations in obese low-birth-weight children. Pedia Obes. 2016;11:285–91.

    Article  Google Scholar 

  7. 7.

    Furman L, Baley J, Borawski-Clark E, Aucott S, Hack M. Hospitalization as a measure of morbidity among very low birth weight infants with chronic lung disease. J Pediatr. 1996;128:447–52.

    CAS  Article  Google Scholar 

  8. 8.

    Barrera-cruz A, Rodríguez-González A, Molina-Ayala MA. Escenario actual de la obesidad en México. Rev Med Inst Mex Seguro Soc. 2013;51:292–9.

    PubMed  Google Scholar 

  9. 9.

    Yuan ZP, Yang M, Liang L, Fu JF, Xiong F, Liu GL, et al. Possible role of birth weight on general and central obesity in Chinese children and adolescents: a cross-sectional study. Ann Epidemiol. 2015;25:748–52.

    Article  Google Scholar 

  10. 10.

    Parsons TJ, Power C, Logan S, Summerbell CD. Childhood predictors of adult obesity: a systematic review. J Pedia Nurs. 2008;23:S1–S107.

    Article  Google Scholar 

  11. 11.

    Ruiz García W, Gurri FD. La doble carga de la transición nutricional en zonas rurales de la frontera sur. In: Ochoa H, editor. La Frontera sur de México, ¿Una salud en crisis? 1st edn. Academia Nacional de Medicina de México: DF, 2018. p 39–48.

  12. 12.

    Gurri FD. The disruption of subsistence agricultural systems in rural Yucatan, Mexico may have contributed to the coexistence of stunting in children with adult overweight and obesity. Coll Antropol. 2015;39:847–54.

    CAS  PubMed  Google Scholar 

  13. 13.

    Doak CM, Adair LS, Bentley M, Monteiro C, Popkin BM. The dual burden household and the nutrition transition paradox. Int J Obes. 2005;29:129–36.

    CAS  Article  Google Scholar 

  14. 14.

    Mendoza-Carrera F, Castro-Martínez XH, Leal C, Portilla-de Buen E, Sánchez-Corona J, Flores-Martínez SE, et al. Analysis of cytokine gene polymorphisms in Mestizo and native populations from Mexico. Am J Hum Biol. 2017;29:1–10.

    Article  Google Scholar 

  15. 15.

    Villarreal Molina MT. Bases geneticas de la variación en los niveles plasmáticos de HDL-colesterol. Rev Endocrinol y Nutr. 2008;16:32–41.

    Google Scholar 

  16. 16.

    Informe anual sobre la situación de pobreza y rezago social. Secretaria de Desarrollo Social. 2017. https://www.gob.mx/cms/uploads/attachment/file/186986/Chiapas.pdf. Accessed 3 Aug 2018.

  17. 17.

    Programa de las Naciones Unidas para el Desarrollo. Índice de Desarrollo Humano Municipal en México: nueva metodología. México, DF: Programa de las Naciones Unidas para el Desarrollo; 2014. https://doi.org/10.1017/CBO9781107415324.004.

  18. 18.

    Instituto Nacional de Estadística y Geografía de México. Principales Resultados de la Encuesta Intercensal 2015 Chiapas. México, DF: INEGI; 2015.

    Google Scholar 

  19. 19.

    González FG, Ochoa H. Una mirada desde el sur sobre los determinantes sociales de la salud. El caso de Chiapas. In: Ochoa H, editor. La Frontera sur de México, ¿Una salud en crisis? 1st edn. Academia Nacional de Medicina de México, DF, 2018. p 179–93.

  20. 20.

    Ramirez-Ortiz MA, Rodriguez-Almaraz M, Ochoa H, Diaz-Prieto P. Randomised equivalency trial comparing 2.5% povidone-iodine eye drops and ophthalmic chloramphenicol for preventing neonatal conjunctivitis in a trachoma endemic area in southern Mexico. Br J Ophthalmol. 2007;91:1430–4.

    Article  Google Scholar 

  21. 21.

    Habitcht JP. Estandarización de métodos epidemiológicos cuantitativos sobre el terreno. Bo!etin la Sanit Panam. 1974;76:375–84.

    Google Scholar 

  22. 22.

    López-González D, Miranda-Lora A, Klünder-Klünder M, Queipo-García G, Bustos-Esquivel M, Paez-Villa M, et al. Diagnostic performance of waist circumference measurements for predicting cardiometabolic risk in Mexican children. Endocr Pract. 2016;22:1170–6.

    Article  Google Scholar 

  23. 23.

    de Onis M, Onyango AW, Borghi E, Siyam A, Nishidaa C, Siekmanna J. Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ. 2007;85:660–7.

    Article  Google Scholar 

  24. 24.

    Thompson O, Vega L. Sensibilidad y especificidad del índice ponderal de Rohrer en el diagnóstico de la desnutrición intrauterina. Rev Mex Pediatr. 2000;67:255–8.

    Google Scholar 

  25. 25.

    Adebami OJ, Owa JA. Comparison between CANSCORE and other anthropometric indicators in fetal malnutrition. Indian J Pediatr. 2008;75:439–42.

    Article  Google Scholar 

  26. 26.

    Aderinsola O, Joseph A. Looking for the best indicator fetal malnutrition: an overview. Internet J Nutr Wellness. 2006;3:1–5.

    Google Scholar 

  27. 27.

    Dunn O. Multiple comparisons among means. J Am Stat Assoc. 1961;56:52–64.

    Article  Google Scholar 

  28. 28.

    Documento normativo sobre bajo peso al nacer. Organización Mundial de la Salud; 2017 http://apps.who.int/iris/bitstream/handle/10665/255733/WHO_NMH_NHD_14.5_spa.pdf. Accessed 3 August 3 2018.

  29. 29.

    Gutierrez JP, Rivera-Domarco J, Shamah-Levy T, Villalpando-Hernández S, Franco A, Cuevas-Nasu L, et al. Encuesta Nacional de Salud y Nutrición 2012. Resultados Nacionales. (Instituto Nacional de Salud Pública, Cuernavaca, 2012).

  30. 30.

    Nutrición Porcentaje de nacidos vivos con bajo peso al nacer por entidad federativa, 2002 a 2012. INEGI; 2016. www3.inegi.org.mx/sistemas/sisept/default.aspx%3Ft%3Dmsal08%26s%3Dest%26c%3D27035+&cd=1&hl=es&ct=clnk&gl=mx. Accessed 28 October 2018.

  31. 31.

    Zepeda-Monreal J, Rodriguez-Balderrama I, Ochoa-Correa E, De la O-Cavazos M, Ambriz-López R. Crecimiento intrauterino. Rev Med Inst Mex Seguro Soc. 2012;50:173–81.

    PubMed  Google Scholar 

  32. 32.

    Rybertt T, Azua E, Rybertt F. Retardo De Crecimiento Intrauterino: Consecuencias a Largo Plazo. Rev Med Clin Condes. 2016;27:509–13.

    Google Scholar 

  33. 33.

    Meneses Alvarez ME, Garcia Parra E, Pérez Herrera A, Irecta Nájera CA Malnutrición y enfermedades metabólicas asociadas. In: Ochoa H, editor. La Frontera sur de México, ¿Una salud en crisis?. 1st edn. Academia Nacional de Medicina de México, DF, 2018. p 3–24.

  34. 34.

    García-Parra E, Ochoa-Díaz-López H, García-Miranda R, Moreno-Altamirano L, Morales H, Estrada-Lugo EI, et al. Estado nutricio de dos generaciones de hermanos(as) < de 5 años de edad beneficiarios(as) de Oportunidades, en comunidades rurales marginadas de Chiapas, México. Nutr Hosp. 2015;31:2685–91.

    PubMed  Google Scholar 

  35. 35.

    Hernández M, Rivera J, Shamah-Levy T, Cuevas L, Gómez L, Gaona E, et al. Encuesta Nacional de Salud y Nutrición de Medio Camino 2016. (Instituto Nacional de Salud Pública, Cuernavaca, 2016).

  36. 36.

    González Rosendo VillanuevaSánchezJ, Alcantar Rodríguez V, Quintero Gutiérrez A. Sobrepeso y obesidad en niños y adolescentes de escuelas de tiempo completo de Morelos, México. Nutr Hosp. 2015;32:2588–93.

    PubMed  Google Scholar 

  37. 37.

    Cerda R, Gálvez P, Palomino A, Vásquez F, Morales G, Andrade M, et al. Concordancia entre índice cintura-talla y otros criterios para clasificar obesidad abdominal en escolares chilenos. Rev Esp Nutr Comunitaria. 2013;19:13–19.

    Google Scholar 

  38. 38.

    Rodea-Montero ER, Evia-Viscarra ML, Apolinar-Jiménez E. Waist-to-Height ratio is a better anthropometric index than waist circumference and BMI in predicting metabolic syndrome among obese mexican adolescents. Int J Endocrinol. 2014; 2014: 195407.

  39. 39.

    Rivera J, Shamah T. Análisis crítico de la evolución de la mala nutrición durante las últimas décadas en México: Resultados de niños. Salud Publica Mex. 2007;49:267–9.

    Google Scholar 

  40. 40.

    Ortiz Hernández L. Estado nutricio en adolescentes de una población suburbana de la ciudad de México Pediatría Revista Mexicana de. Rev Mex Pediatr. 2003;70:109–17.

    Google Scholar 

  41. 41.

    López-Rodríguez G, Galván M, Fuentes GS. Indicadores de síndrome metabólico en escolares mexicanos con talla baja, sobrepeso u obesidad. Arch Lat Nutr. 2016;66:309–17.

    Google Scholar 

  42. 42.

    Chaudhari S, Otiv M, Hoge M, Pandit A, Mote A. Growth and sexual maturation of low birth weight infants at early adolescence. Indian Paediatr. 2008;45:191–8.

    Google Scholar 

  43. 43.

    Hermanussen M. Stunted growth. Eur J Clin Nutr. 2016;70:647–9.

    CAS  Article  Google Scholar 

  44. 44.

    Dewey KG, Begum K. Long-term consequences of stunting in early life. Matern Child Nutr. 2011;7:5–18.

    Article  Google Scholar 

  45. 45.

    Martorell R, Khan LK, Schroeder DG. Reversibility of stunting: epidemiological findings in children from developing countries. Eur J Clin Nutr. 1994;48:s45–57.

    PubMed  Google Scholar 

  46. 46.

    Stern MP, Bartley M, Duggirala R, Bradshaw B. Birth weight and the metabolic syndrome: thrifty phenotype or thrifty genotype? Diabetes Metab Res Rev. 2000;16:88–93.

    CAS  Article  Google Scholar 

  47. 47.

    Prendergast AJ, Humphrey JH. The stunting syndrome in developing countries. Paediatr Int Child Health. 2014;34:250–65.

    Article  Google Scholar 

  48. 48.

    Monteiro PO, Victora CG, Barros FC, Monteiro LM. Birth size, early childhood growth, and adolescent obesity in a Brazilian birth cohort. Int J Obes Relat Metab Disord. 2003;27:1274–82.

    CAS  Article  Google Scholar 

  49. 49.

    Varela-Silva MI, Azcorra H, Dickinson F, Bogin B, Frisancho AR. Influence of maternal stature, pregnancy age, and infant birth weight on growth during childhood in Yucatan, Mexico: a test of the intergenerational effects hypothesis. Am J Hum Biol. 2009;21:657–63.

    Article  Google Scholar 

Download references

Acknowledgements

We are grateful to the families who participated in this study. Fieldwork activities were achieved thanks to the contribution of nutritional students from Universidad de Ciencias y Artes de Chiapas and medical students from Universidad del Sureste and Instituto de Estudios Superiores de Chiapas.

Funding

This study was supported by CONACYT. EFG received a PhD scholarship from PRODEP. IC-Q received a postdoctoral scholarship from CONACYT.

Author information

Affiliations

Authors

Contributions

HODL conceived and directed the project. EFG, HODL and CAIN designed and planned the study. EFG supervised data collection. RSH performed statistical analysis. HODL, EFG and ICQ contributed to the analysis and interpretation of the results. EFG and HODL wrote the draft of the paper with input from all the authors. MCL, FDG, MEM and RGM reviewed critically the paper. All authors approved the final version.

Corresponding author

Correspondence to Héctor Ochoa-Díaz-López.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Flores-Guillén, E., Ochoa-Díaz-López, H., Castro-Quezada, I. et al. Intrauterine growth restriction and overweight, obesity, and stunting in adolescents of indigenous communities of Chiapas, Mexico. Eur J Clin Nutr 74, 149–157 (2020). https://doi.org/10.1038/s41430-019-0440-y

Download citation

Further reading

Search

Quick links