Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Clinical nutrition

Coffee consumption in hemodialysis patients: how many?


Background and aims

Coffee is one of the most widely consumed beverages worldwide. However, fluid intake restriction is an important and difficult challenge for hemodialysis (HD) patients. The aim of this study was to analyze the effect of coffee intake on hydration and nutritional parameters of HD patients.


This was an observational, cross-sectional, multicenter study where 373 HD patients from 8 dialysis centers in Portugal were enrolled. A face-to-face questionnaire was applied and patient’s clinical and body composition parameters were analyzed. The sample was divided into 3 groups depending on coffee intake: group 1—don’t drink coffee, group 2—drink 1–2 coffees/day and group 3—drink 3 or more coffees/day. Laboratory and body composition parameters were registered in the month prior to the questionnaire application. Body composition was assessed with the Body Composition Monitor (BCM; Fresenius Medical Care Deutschland GmbH, Germany).


Patient’s mean age was 67.2 ± 14.4 years and the mean HD vintage was 61.3 ± 56.2 months. Patients who reported drinking 3 or more coffees daily were younger, presented higher levels of potassium, phosphorus, diastolic BP, albumin and interdialytic weight gain (IDWG) and lower dialysis adequacy (Kt/V). Regarding body composition, patients in the group 3 showed higher body cell mass index (BCMI) and lean tissue index (LTI). On the other hand, the group 1 were the oldest, had a higher Kt/V, a lower diastolic blood pressure (BP) and potassium levels, whereas G2 presented a lower LTI, BCMI and IDWG.


Drinking 3 or more coffees daily increases the risk of a higher diastolic BP, potassium and IDWG in HD patients.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type



Prices may be subject to local taxes which are calculated during checkout


  1. Kalantar-Zadeh K, Regidor DL, Kovesdy CP, Van Wyck D, Bunnapradist S, Horwich TB, et al. Fluid retention is associated with cardiovascular mortality in patients undergoing long-term hemodialysis. Circulation. 2009;119(5):671–9.

    Article  Google Scholar 

  2. Wizemann V, Wabel P, Chamney P, Zaluska W, Moissl U, Rode C, et al. The mortality risk of overhydration in haemodialysis patients. Nephrol Dial Transplant. 2009;24(5):1574–9.

    Article  Google Scholar 

  3. Albayrak Cosar A, Cinar Pakyuz S. Scale development study: the fluid control in hemodialysis Patients. Jpn J Nurs Sci. 2016;13(1):174–82.

    Article  Google Scholar 

  4. Molto CI, Iborra-Molto C, Lopez-Roig S, Mira M, de LAP. Prevalence of adherence to fluid restriction in kidney patients in haemodialysis: objective indicator and perceived compliance. Nefrologia. 2012;32(4):477–85.

    Google Scholar 

  5. Higdon JV, Frei B. Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr. 2006;46(2):101–23.

    Article  CAS  Google Scholar 

  6. Zainab S, Djafarian K. Coffee consumption and coronary heart diseases: a mini-review. J Clin Nutr Diet. 2016;2:1–7.

    Google Scholar 

  7. Nikić PM, Andrić BR, Stojimirović BB, Trbojevic-Stanković J, Bukumirić Z. Habitual coffee consumption enhances attention and vigilance in hemodialysis patients. Biomed Res Int. 2014;2014:1–7.

    Article  Google Scholar 

  8. Barbosa M, Carvalho T. 5 Questões sobre Café. 2016.

  9. Porto A, Oliveira L. Tabela da Composição de Alimentos. Instituto Nacional de Saúde Dr. Ricardo Jorge. Plataforma Portuguesa de Informação Alimentar, 2016. Available on:

  10. Grosso G, Godos J, Galvano F, Giovannucci EL. Coffee, caffeine, and health outcomes: an umbrella review. Annu Rev Nutr. 2017;37(1):131–56.

    Article  CAS  Google Scholar 

  11. Fouque D, Vennegoor M, Wee P Ter, Wanner C, Basci A, Canaud B. et al. EBPG guideline on nutrition. Nephrol Dialysis Transplant. 2007;22:45–87.

    Article  Google Scholar 

  12. Ghaddar S, Shamseddeen W, Elzein H. Behavioral modeling to guide adherence to fluid control in hemodialysis patients. J Ren Nutr. 2009;19(2):153–60.

    Article  Google Scholar 

  13. Grosso G, Stepaniak U, Polak M, Micek A, Topor-Madry R, Stefler D, et al. Coffee consumption and risk of hypertension in the Polish arm of the HAPIEE cohort study. Eur J Clin Nutr. 2016;70(1):109–15.

    Article  CAS  Google Scholar 

  14. Bae J-H, Park J-H, Im S-S, Song D-K. Coffee and health. Integr Med Res. 2014;3(4):189–91.

    Article  Google Scholar 

  15. Clark I, Landolt HP. Coffee, caffeine, and sleep: A systematic review of epidemiological studies and randomized controlled trials. Sleep Med Rev. 2017;31:70–8.

    Article  Google Scholar 

  16. Mesas AE, Leon-Muñoz LM, Rodriguez-Artalejo F, Lopez-Garcia E. The effect of coffee on blood pressure and cardiovascular disease in hypertensive individuals: a systematic review and meta-analysis. Am J Clin Nutr. 2011;94(4):1113–26.

    Article  CAS  Google Scholar 

  17. Geleijnse JM. Habitual coffee consumption and blood pressure: an epidemiological perspective. Vasc Health Risk Manag. 2008;4:963–70.

    Article  Google Scholar 

  18. Grosso G, Micek A, Godos J, Pajak A, Sciacca S, Bes-Rastrollo M. et al. Long-term coffee consumption is associated with decreased incidence of new-onset hypertension: a dose–response meta-analysis. Nutrients. 2017;9:1–13.

    Article  Google Scholar 

  19. Noguchi K, Matsuzaki T, Sakanashi M, Hamadate N, Uchida T, Kubota H. et al. Effect of caffeine contained in a cup of coffee on microvascular function in healthy subjects. J Pharmacol Sci. 2015;127:217–22.

    Article  CAS  Google Scholar 

  20. Simone de G, Pasanisi F. Systolic, diastolic pulse press: pathophysiology. Ital Hear J Suppl J. 2001;2(4):359–62.

    Google Scholar 

  21. Song JH, Park GH, Lee SY, Lee SW, Lee SW, Kim MJ. Effect of sodium balance and the combination of ultrafiltration profile during sodium profiling hemodialysis on the maintenance of the quality of dialysis and sodium and fluid balances. J Am Soc Nephrol. 2005;16(1):237–46.

    Article  Google Scholar 

  22. Grzegorzewska AE, Młot-Michalska M. Coffee consumption and bone mineral density in dialysis patients. Adv Perit Dial Conf Perit Dial. 2008;24:84–9.

    CAS  Google Scholar 

  23. Grzegorzewska AE, Młot-Michalska M, Wobszal P. Does ingestion of regular coffee influence serum lipid profile in dialysis patients? Adv Perit Dial. 2009;25:181–6.

    PubMed  Google Scholar 

  24. Petrušić N, Posavac M, Sabol I, Mravak-Stipetić M. The effect of tobacco smoking on salivation. Acta Stomatol Croat. 2015;49(4):309–15.

    Article  Google Scholar 

  25. Bossola M, Tazza L. Xerostomia in patients on chronic hemodialysis. Nat Rev Nephrol. 2012;8:176–82.

    Article  CAS  Google Scholar 

Download references


This study was approved by the local responsible of the ethical board and an informed written consent was previously signed by the patients. All the authors work at Nephrocare dialysis units in Portugal. We certify that the results presented in this paper have not been published previously in whole or part, except in abstract form.

Author information

Authors and Affiliations


Corresponding author

Correspondence to Cristina Caetano.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and Permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Caetano, C., Valente, A., Oliveira, T. et al. Coffee consumption in hemodialysis patients: how many?. Eur J Clin Nutr 73, 924–929 (2019).

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI:


Quick links