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Human body composition: yesterday, today, and tomorrow

European Journal of Clinical Nutrition volume 72, pages 1201–1207 (2018)Cite this article

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The composition of the body, at any point in time, captures the outcome of all prior influences upon human physiology that have led to the accumulation of all these different constituents up to that point [1]. Other than the underlying genetic milieu, principal among these influences are nutrition and illness. Body composition represents an historic record of life’s balance of energy and nutrient intake. When nutritional intake is mismatched to requirement change in body composition occurs. For example, it has long been recognised that inadequate nutrition may lead to altered body composition as seen in wasting and stunting [1], while, conversely, over-nutrition leads to obesity particularly in children in populations undergoing nutritional transition [2]. Similarly, body composition may be adversely affected by ill-health, e.g., surgical trauma may lead to short-term loss of lean mass while long-term infection with tuberculosis is associated with wasting [3]. The composition of the body, as well as being a reflection of nutritional experience, is also a gauge of body function. Optimal bodily functioning and good health demand a body composition that provides the ideal masses of tissues and organs that support the physiological and biochemical processes that underpin a healthy life. These two factors are not independent; nutrition impacts upon body composition which in turn impacts on bodily function. Knowledge of body composition provides insights into both nutritional status and functional capacity of the human body.

The analysis of body composition has a long and rich history (those interested in a detailed account of the history of body composition analysis are referred to Wang et al. [4]). The first quantitative studies of the human body date to early cadaver analyses in the 1840s. The obvious drawback of cadaver analysis is that it can only be undertaken at time of death and can only provide retrospective information. Since the early part of the 20th century, few cadaver studies have been undertaken, with the notable exception of the work of Clarys and colleagues [5], and the focus has been on the development of technologies for the quantitative assessment of body composition in vivo (Table 1). One of the first measurements, by Shaffer and Coleman in 1909 [4], was the estimation of muscle mass from the measurement of the excretion rate of creatinine, but the real advance came with the availability of isotopes of atoms of nutritional interest.

Table 1 Characteristics of techniques used for body composition analysis
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References

  1. Jackson AA, Johnson M, Durkin K, Wootton S. Body composition assessment in nutrition research: value of BIA technology. Eur J Clin Nutr. 2013;67:S71–8. https://doi.org/10.1038/ejcn.2012.167.

    Article  PubMed  Google Scholar 

  2. Piernas C, Wang D, Du S, Zhang B, Wang Z, Su C, et al. The double burden of under- and overnutrition and nutrient adequacy among Chinese preschool and school-aged children in 2009-2011. Eur J Clin Nutr. 2015;69:1323–9.

    Article  CAS  Google Scholar 

  3. Villamor E, Saathoff E, Mugusi F, Bosch RJ, Urassa W, Fawzi WW. Wasting and body composition of adults with pulmonary tuberculosis in relation to HIV-1 coinfection, socioeconomic status, and severity of tuberculosis. Eur J Clin Nutr. 2006;60:163–71.

    Article  CAS  Google Scholar 

  4. Wang Z, Wang Z-M, Heymsfield SB. History of the study of human body composition: a brief review. J Hum Biol. 1999;11:157–65.

    Article  CAS  Google Scholar 

  5. Clarys JP, Martin AD,Drinkwater DT. Gross tissue weights in the human body by cadaver dissection. Hum Biol. 1984;56:459–73. http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=6489991.

    CAS  PubMed  Google Scholar 

  6. Hevesy G, Hofer R. Elimination of water from the human body. Nature. 1934;134:879.

    Article  Google Scholar 

  7. Dempster P, Aitkens S. A new air displacement method for the determination of human body composition. Med Sci Sport Exerc. 1995;27:1692–7.

    Article  CAS  Google Scholar 

  8. McCrory MA, Gomez TD,Bernauer EM,Molé PA. Evaluation of a new air displacement plethysmograph for measuring human body composition. Med Sci Sports Exerc. 1995;27:1686–91.http://ovidsp.tx.ovid.com.ezproxy.nottingham.ac.uk/sp-3.18.0b/ovidweb.cgi?WebLinkFrameset=1&S=DMPCFPHBFEDDDAOMNCJKJBOBPCHEAA00&returnUrl=ovidweb.cgi%3FMain%2BSearch%2BPage%3D1%26S%3DDMPCFPHBFEDDDAOMNCJKJBOBPCHEAA00&directlink=http%3A%2F%2Fgraphics.tx.ovid.

    Article  CAS  Google Scholar 

  9. Kyle UG, Bosaeus I, De Lorenzo AD, Deurenberg P, Elia M, Gómez JM, et al. Bioelectrical impedance analysis—part I: review of principles and methods. Clin Nutr. 2004;23:1226–43.

    Article  Google Scholar 

  10. Kyle UG, Bosaeus I, De Lorenzo AD, Go M, Lilienthal B, Deurenberg P et al. Bioelectrical impedance analysis-part II: utilization in clinical practice. Clin Nutr Edinburgh Scotl. 2004. http://www.ncbi.nlm.nih.gov/pubmed/15380917.

  11. Murphy AJ, Ellis KJ, Kurpad AV, Preston T, Slater C. Total body potassium revisited. Eur J Clin Nutr. 2014;68:153–4. https://doi.org/10.1038/ejcn.2013.262%5Cnhttp://search.ebscohost.com/login.aspx?direct=true&db=a9h&AN=94277769&site=ehost-live.

    Article  CAS  PubMed  Google Scholar 

  12. Pierson RN. A brief history of body composition—from F.D. Moore to the new reference man. Acta Diabetol. 2003;40:114–6.

    Article  Google Scholar 

  13. Thibault R, Genton L, Pichard C. Body composition: why, when and for who? Clin Nutr. 2012. http://www.ncbi.nlm.nih.gov/pubmed/22296871.

  14. Andreoli A, Garaci F,Cafarelli FP,Guglielmi G. Body composition in clinical practice. Eur J Radiol. 2016;85:1461–8.http://www.ncbi.nlm.nih.gov/pubmed/26971404.

    Article  Google Scholar 

  15. Müller MJ, Bosy-Westphal A, Later W, Haas V, Heller M. Functional body composition: insights into the regulation of energy metabolism and some clinical applications. Eur J Clin Nutr. 2009;63:1045–56.

    Article  Google Scholar 

  16. Gallagher D, Albu J, He Q, Heshka S, Boxt L, Krasnow N, et al. Small organs with a high metabolic rate explain lower resting energy expenditure in African American than in white adults. Am J Clin Nutr. 2006;83:1062–7.

    Article  CAS  Google Scholar 

  17. Borga M, West J, Bell JD, Harvey NC, Romu T, Heymsfield SB et al. Advanced body composition assessment: from body mass index to body composition profiling. J Investig Med. 2018. http://jim.bmj.com/content/early/2018/03/24/jim-2018-000722.abstract.

  18. Bourgeois B, Ng BK, Latimer D, Stannard CR, Romeo L, Li X, et al. Clinically applicable optical imaging technology for body size and shape analysis: comparison of systems differing in design. Eur J Clin Nutr. 2017;71:1329–35.

    Article  CAS  Google Scholar 

  19. Heymsfield SB, Pietrobelli A,Wang Z,Saris WHM. The end of body composition methodology research? Curr Opin Clin Nutr Metab Care. 2005;8:591–4. http://www.ncbi.nlm.nih.gov/pubmed/16205457.

    Article  CAS  Google Scholar 

  20. Talwar Y, Karthikeyan S. Smartphone—a user-friendly device to deliver affordable healthcare—a practical paradigm. J Heal Med Informatics. 2016. https://www.omicsonline.org/open-access/smartphone--a-userfriendly-device-to-deliver-affordable-healthcare--apractical-paradigm-2157-7420-1000232.php?aid=74665.

  21. Choi A, Kim JY, Jo S, Jee JH, Heymsfield SB, Bhagat YA, et al. Smartphone-based bioelectrical impedance analysis devices for daily obesity management. Sensors. 2015;15:22151–66.

    Article  Google Scholar 

  22. Lee Y-G, Jeong WS,Yoon G. Smartphone-based mobile health monitoring. Telemed e-Health. 2012;18:585–90.http://online.liebertpub.com/doi/abs/10.1089/tmj.2011.0245.

    Article  Google Scholar 

  23. Heymsfield SB, Kim JY, Bhagat YA, Zheng J, Choi A, Jo S et al. Mobile evaluation of human energy balance and weight control:potential for future developments. Conf Proc IEEE Eng Med Biol Soc. 2015;2015:8201–4. https://doi.org/10.1109/EMBC.2015.7320298.

  24. Farina GL, Spataro F, de Lorenzo A, Lukaski H. A smartphone application for personal assessments of body composition and phenotyping. Sensors (Basel). 2016;16:2163.

    Article  Google Scholar 

  25. Villa F, Magnani A, Maggioni MA, Stahn A, Rampichini S, Merati G et al. Wearable multi-frequency and multi-segment bioelectrical impedance spectroscopy for unobtrusively tracking body fluid shifts during physical activity in real-field applications: a preliminary study. 2016:16050673.

  26. Lee CH, Yoon H-J. Medical big data: promise and challenges. Kidney Res Clin Pract. 2017;36:3–11.

    Article  Google Scholar 

  27. Wootton S, Durkin K, Jackson A. Quality control issues related to assessment of body composition. Food Nutr Bull. 2014;35:S79–85.

    Article  Google Scholar 

  28. González-Correa CH,Caicedo-Eraso JC. Bioelectrical impedance analysis (BIA): a proposal for standardization of the classical method in adults. J Phys Conf Ser. 2012;407:12018. http://stacks.iop.org/1742-6596/407/i=1/a=012018?key=crossref.fdb722c334700f288fc85db2dc7015ab.

    Article  Google Scholar 

  29. Brantlov S, LCLC Ward, Jødal L, Rittig S, Lange A. Critical factors and their impact on bioelectrical impedance analysis in children: a review. J Med Eng Technol. 2017;41:22–35.

    Article  Google Scholar 

  30. Brantlov S, Jødal L, Lange A, Rittig S, Ward LC, Brantlov S, et al. Standardisation of bioelectrical impedance analysis for the estimation of body composition in healthy paediatric populations: a systematic review. J Med Eng Technol. 2017;0:1–20. https://doi.org/10.1080/03091902.2017.1333165.

    Article  Google Scholar 

  31. Sardinha LB. Functional body composition: need for a new agenda. Arch Exerc Heal Dis. 2012;3:183–7.

    Article  Google Scholar 

  32. Müller MJ, Baracos V, Bosy-Westphal A, Dulloo AG, Eckel J, Fearon KCH et al. Functional body composition and related aspects in research on obesity and cachexia: Report on the 12th Stock Conference held on 6 and 7 September 2013 in Hamburg, Germany. Obes Rev. 2014;15:640–56.

    Article  Google Scholar 

  33. Vartsky D,Ellis KJ, Cohn SH. In vivo measurement of body nitrogen by analysis of prompt gammas from neutron capture. J Nucl Med. 1979;20:1158–65.http://www.ncbi.nlm.nih.gov/pubmed/536776.

    CAS  PubMed  Google Scholar 

  34. Wilson JP, Strauss BJ, Fan B, Duewer FW, Shepherd JA. Improved 4-compartment body-composition model for a clinically accessible measure of total body protein. Am J Clin Nutr. 2013;97:497–504.

    Article  CAS  Google Scholar 

  35. Wang Z-M, Pierson RN, Heymsfield S. The five-level model: a new approach to organizing. Am J Clin Nutr. 1992;56:19–28.

    Article  CAS  Google Scholar 

  36. Wang ZM, Deurenberg P, Guo SS, Pietrobelli A, Wang J, Pierson RN, et al. Six-compartment body composition model: inter-method comparisons of total body fat measurement. Int J Obes Relat Metab Disord. 1998;22:329–37.

    Article  CAS  Google Scholar 

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  1. School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, 4072, Australia

    Leigh C. Ward

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Ward, L.C. Human body composition: yesterday, today, and tomorrow. Eur J Clin Nutr 72, 1201–1207 (2018). https://doi.org/10.1038/s41430-018-0210-2

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