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Phaeolschidin F, a new symmetrical bis(styrylpyrone) derivative with redox-catalyzing activity from the mushroom Gymnopilus aeruginosus (order Agaricales)


Phaeolschidin F (1) was isolated from fruiting bodies of the bitter and toxic mushroom Gymnopilus aeruginosus. Structure analysis by NMR and MS revealed that 1 is a new symmetrical bis(styrylpyrone). A series of anti-oxidant and pro-oxidant tests characterized that 1 is a redox catalyst having more anti-oxidant and less pro-oxidant activities than quercetin.

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This work was supported in part by President’s Fund Initiative 2020 (Science for Local Community) at Toyama Prefectural University.

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Correspondence to Naoya Oku.

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Supporting Information for: Phaeolschidin F, a new symmetrical bis(styrylpyrone) derivative with redox-catalyzing activity from the mushroom <i>Gymnopilus aeruginosus</i> (order <i>Agaricales</i>)

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Oku, N., Netsu, R., Kurokawa, Y. et al. Phaeolschidin F, a new symmetrical bis(styrylpyrone) derivative with redox-catalyzing activity from the mushroom Gymnopilus aeruginosus (order Agaricales). J Antibiot 76, 236–238 (2023).

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