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Trehangelin E, a bisacyl trehalose with plant growth promoting activity from a rare actinomycete Polymorphospora sp. RD064483

The Journal of Antibiotics volume 75, pages 296–300 (2022)Cite this article

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Abstract

Trehangelin E (1), a new bisacyl trehalose, was isolated from the culture extract of an actinomycete Polymorphospora sp. RD064483, along with three known congeners, trehangelins A, B, and D. Compound 1 is a new trehalose derivative acylated with (Z)-2-methyl-2-butenoic acid (angelic acid) at 3- and 6ʹ-positions, as determined by NMR and MS analyses. Compound 1 promoted root elongation of germinated lettuce seeds by 30% at 1 μM and 90% at 10 μM compared to the nontreated seeds. Similar promoting activity of root elongation was also observed with trehangelins A and B at the same level.

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Acknowledgements

This work was supported by JSPS KAKENHI Grant Number 24580156 to YI.

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  1. Biotechnology Research Center and Department of Biotechnology, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama, 939-0398, Japan

    Shiyang Lu, Enjuro Harunari, Naoya Oku & Yasuhiro Igarashi

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  1. Shiyang Lu
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  2. Enjuro Harunari
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Correspondence to Yasuhiro Igarashi.

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Trehangelin E, a bisacyl trehalose with plant growth promoting activity from a rare actinomycete Polymorphospora sp. RD064483

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Lu, S., Harunari, E., Oku, N. et al. Trehangelin E, a bisacyl trehalose with plant growth promoting activity from a rare actinomycete Polymorphospora sp. RD064483. J Antibiot 75, 296–300 (2022). https://doi.org/10.1038/s41429-022-00519-5

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