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Formation of a glyco-functionalized interface on polyethylene using a side-chain crystalline block copolymer with epoxide

Polymer Journal volume 54, pages 1103–1109 (2022)Cite this article

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Abstract

A side-chain crystalline block copolymer was applied for the chemical modification of polyethylene surfaces. A block copolymer with stearyl and epoxy groups was prepared by nitroxide-mediated living radical polymerization. This copolymer had a phase transition temperature of ~40 °C. When the side-chain crystalline block copolymer was immobilized on polyethylene, a polymeric layer with nucleophilic reactivity was formed. The layer thickness increased with increasing copolymer concentration. Galactoside ligands were added to the polymeric layer by the ring-opening addition reaction of the epoxide. The obtained glyco-functionalized interface exhibited specific protein binding; the polyethylene surface containing galactoside ligands was adsorbed to peanut agglutinin rather than wheat germ agglutinin.

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Acknowledgements

This study was supported by JSPS KAKENHI (grant number 19K05042). This study was funded by the Shiraishi Scientific Research Fund of Fukuoka University (No. SK2001) and the Central Research Institute of Fukuoka University (Nos. 165005, 175009, and 207103). We thank Nihon Kasei Co., Ltd. for providing the 4HBAGE. We thank Alkema Inc. for providing BlocBuilder® MA. XPS measurements were conducted by Dr. T. Murakami and Mr. I. Kimura of JAIST, supported by the Nanotechnology Platform Program (Molecule and Material Synthesis) of the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. We are grateful for the assistance of Prof. Y. Miura (Kyushu University) in providing access to the UV–Vis spectrophotometer. We thank Mr. Y. Nagano and Mr. S. Aso for their cooperation in the experiments.

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  1. Department of Chemical Engineering, Fukuoka University, 8-19-1 Nanakuma, Jonan, Fukuoka, 814-0180, Japan

    Hirokazu Seto, Mayu Yasunaga, Nami Mawatari, Yumiko Hirohashi, Shigeru Yao & Hiroyuki Shinto

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  1. Hirokazu Seto
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  2. Mayu Yasunaga
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Correspondence to Hirokazu Seto.

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Seto, H., Yasunaga, M., Mawatari, N. et al. Formation of a glyco-functionalized interface on polyethylene using a side-chain crystalline block copolymer with epoxide. Polym J 54, 1103–1109 (2022). https://doi.org/10.1038/s41428-022-00652-w

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