Fig. 3 | NPG Asia Materials

Fig. 3

From: A batch-by-batch free route for the continuous production of black phosphorus nanosheets for targeted combination cancer therapy

Fig. 3

Cytotoxicity profiles of D, BP-DLH, and BP-DLH after NIR irradiation in MCF-7 (a) and MDA-MB-231 (b) cells. Insets show the profiles for BP-LH in the absence or presence of NIR irradiation. c Confocal images of MCF-7 and MDA-MB-231 cells incubated with FITC-labeled BP-DLH with and without H pretreatment. Lysotracker Red was used for staining lysosomes and endosomes. d FACS analyses to examine the cellular uptake of FITC-labeled BP-LH for different incubation times with and without H pretreatment. e Hemolysis from treatment with BP and BP-LH. The inset shows relevant digital images from the hemolysis tests. f Live/dead assay of BP-LH incubated with MCF-7 and MDA-MB-231 cells following NIR irradiation. EthD-1 stains dead cells red, and calcein-AM stains live cells green. g Apoptosis of MCF-7 and MDA-MB-231 cells (i) after treatment with (ii) free D (iii) BP-DLH or (iv) BP-DLH with NIR irradiation

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