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Single-chain variable fragment antibody constructs neutralize measles virus infection in vitro and in vivo

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Acknowledgements

We thank J. S. Orange and S. G. Kernie for their contributions to this study.

Funding

The work was supported by grants from the NIH: AI121349, NS091263, and NS105699, AI146980 to M.P., from the French ANR NITRODEP (ANR-13-PDOC-0010-01) to C.M. and from the Region Auvergne Rhone Alpes and LABEX ECOFECT (ANR-11-LABX-0048) of Lyon University within the program “Investissements d'Avenir” (ANR-11-IDEX-0007), operated by the French National Research Agency (ANR) to B.H. The Sharon Golub Fund at Columbia University Irving Medical Center (CUIMC).

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Correspondence to Cyrille Mathieu or Matteo Porotto.

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C.M., A.M., B.H., and M.P. have submitted a provisional on the use of the scFv.

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Mathieu, C., Ferren, M., Harder, O. et al. Single-chain variable fragment antibody constructs neutralize measles virus infection in vitro and in vivo. Cell Mol Immunol (2021). https://doi.org/10.1038/s41423-021-00691-y

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