Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

A new predictive biomarker enables more accurate PD-1 blockade therapy

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Fig. 1


  1. 1.

    Kumagai, S. et al. Nat. Immunol. 21, 1346–1358 (2020).

    CAS  Article  Google Scholar 

  2. 2.

    Ahmadzadeh, M. et al. Blood 114, 1537–1544 (2009).

    CAS  Article  Google Scholar 

  3. 3.

    Yokosuka, T. et al. J. Exp. Med. 209, 1201–1217 (2012).

    CAS  Article  Google Scholar 

  4. 4.

    Hui, E. et al. Science 355, 1428–1433 (2017).

    CAS  Article  Google Scholar 

  5. 5.

    Kansy, B. A. et al. Cancer Res. 77, 6353–6364 (2017).

    CAS  Article  Google Scholar 

  6. 6.

    Gros, A. et al. J. Clin. Invest. 124, 2246–2259 (2014).

    CAS  Article  Google Scholar 

  7. 7.

    Daud, A. I. et al. J. Clin. Invest. 126, 3447–3452 (2016).

    Article  Google Scholar 

  8. 8.

    Thommen, D. S. et al. Nat. Med. 24, 994–1004 (2018).

    CAS  Article  Google Scholar 

  9. 9.

    Lowther, D. E. et al. JCI Insight 1, e85935 (2016).

    Article  Google Scholar 

  10. 10.

    Kamada, T. et al. Proc. Natl Acad. Sci. USA 116, 9999–10008 (2019).

    CAS  Article  Google Scholar 

Download references

Author information



Corresponding author

Correspondence to Sheng Jiang.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Zhang, K., Jiang, S. A new predictive biomarker enables more accurate PD-1 blockade therapy. Cell Mol Immunol (2021).

Download citation


Quick links