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The brain–immune cells axis controls tissue specific immunopathology

Cellular & Molecular Immunology volume 16, pages 101–103 (2019)Cite this article

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Abstract

During viral infections, cell death can be induced as a direct result of cytopathic virus replication in various cell types and tissues or as an immune response of the host to the infectious agent. This leads to an infiltration of inflammatory cells, causing subsequent tissue damage. The balance between effective elimination of the pathogen and prevention of fatal tissue damage is decisive for life. The host has developed various mechanisms to inhibit excessive immune responses.

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Authors and Affiliations

  1. Institute for Medical Microbiology and Hospital Hygiene, Otto-von-Guericke University Magdeburg, Magdeburg, Germany

    Maxi Heyner, Sarah Schreier & Andrea Kröger

  2. Innate Immunity and Infection Group, Helmholtz Centre for Infection Research, Braunschweig, Germany

    Andrea Kröger

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  1. Maxi Heyner
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  2. Sarah Schreier
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  3. Andrea Kröger
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Correspondence to Andrea Kröger.

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Heyner, M., Schreier, S. & Kröger, A. The brain–immune cells axis controls tissue specific immunopathology. Cell Mol Immunol 16, 101–103 (2019). https://doi.org/10.1038/s41423-018-0176-y

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