Structural basis of a Tn7-like transposase recruitment and DNA loading to CRISPR-Cas surveillance complex

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Fig. 1: Assembly and target DNA recognition of type I-F Cascade-TniQ complex.

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Acknowledgements

We thank the staff of the BL18U and BL19U1 beamlines of National Center for Protein Science in Shanghai (NCPSS) and BL17U of Shanghai Synchrotron Radiation Facility (SSRF). We thank the staff of Electron Microscopy facility of NCPSS for technical assistance in data collection. This study was supported by the National Natural Science Foundation of China (31971135) to H.Y.

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B.W. performed all the experiments. W.X. helped with the data collection. H.Y. designed the study, wrote the manuscript, and supervised the research.

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Correspondence to Hui Yang.

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The authors declare no competing interests.

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Wang, B., Xu, W. & Yang, H. Structural basis of a Tn7-like transposase recruitment and DNA loading to CRISPR-Cas surveillance complex. Cell Res 30, 185–187 (2020). https://doi.org/10.1038/s41422-020-0274-0

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