Fig. 5: Dynamics of DNA methylation at enhancers. | Cell Discovery

Fig. 5: Dynamics of DNA methylation at enhancers.

From: DNA methylation reprogramming of functional elements during mammalian embryonic development

Fig. 5

a Violin plots of the dynamics for enhancers in humans and mice during early embryogenesis. b Heat map of the methylation reprogramming of enhancers from human gametes to early embryos. An unsupervised hierarchical cluster analysis was performed, and then GO enrichment analysis of each group was performed with GREAT online tools. c Graphical representations of the methylation status of distal enhancers of SOX2 in human gametes and early embryos. The H3K27ac and H3K4me1 datasets came from H1 cells generated by the NIH Roadmap project (the accession numbers are GSM466732 and GSM409307)