Fig. 6: Activation of NLRP3 pathway reverses the protection of ERP 44 against H/R injury. | Cell Death Discovery

Fig. 6: Activation of NLRP3 pathway reverses the protection of ERP 44 against H/R injury.

From: IP3R1 regulates Ca2+ transport and pyroptosis through the NLRP3/Caspase-1 pathway in myocardial ischemia/reperfusion injury

Fig. 6

A CCK-8 was used to detect cell viability; B ELISA was used to detect the levels of IL-1β and IL-18 in cells; C western blot was used to detect the levels of pyroptosis markers in cells. Nig represents an activator of NLRP3. *p < 0.05, **p < 0.01, ***p < 0.001. All experiments were performed three times independently. Data were analyzed using two-way ANOVA and Tukey’s multiple comparison test.

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