Table1 Area under curve (AUC), sensitivity, and specificity of SARS-CoV-2 IgG–IgM serological tests.

From: SARS-CoV-2 infection serology: a useful tool to overcome lockdown?

Positive RT-qPCR sample: 43
Negative RT-qPCR sample: 40
CARD 1 CARD 2 CARD 3 CLIA
IgM IgG IgM IgG IgM IgG IgM IgG
Sensitivity (%) 61.4 84.3 87.8 89.6 84 93 84 95
Specificity (%) 100 100 100 100 100 100 94 100
Kit cut-off Qualitative test >1.3 T/C >1.2 T/C >1 COI >10 COI
Area under the ROC curve (AUC); 95% confidence interval 0.921; 0.830 to 0.969 0.981; 0.918 to 0.999 0.943; 0.863 to 0.983 0.997; 0.945 to 1.000
Sensitivity (%) 84 93 91 95
Specificity (%) 100 100 94 100
Laboratory cut-off >1.28 T/C  > 1.2 T/C  > 0.54 COI  > 10.26 COI